Antibiotic prophylaxis in penetrating colorectal injuries: The comparative effectiveness of clindamycin and cephalothin in combination with an aminoglycoside

O. V. Martinez; J. Lancelot Lester; A. Arango; T. I. Malinin

Antibiotic prophylaxis in penetrating colorectal injuries: The comparative effectiveness of clindamycin and cephalothin in combination with an aminoglycoside

O. V. Martinez, J. Lancelot Lester, A. Arango, T. I. Malinin

Research output: Contribution to journal › Article › peer-review

Abstract

In examining 66 penetrating colorectal injuries in which the peritoneum was almost always exposed to the normal gastrointestinal microflora it appears that both clindamycin and cephalothin were equally effective in maintaining a relatively low rate of postoperative sepsis when administered early, in combination with an aminoglycoside agent and in addition to intra-operative antibiotic irrigation.

Original language	English (US)
Pages (from-to)	378-383
Number of pages	6
Journal	American Surgeon
Volume	45
Issue number	6
State	Published - Dec 1 1979

ASJC Scopus subject areas

Surgery

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title = "Antibiotic prophylaxis in penetrating colorectal injuries: The comparative effectiveness of clindamycin and cephalothin in combination with an aminoglycoside",

abstract = "In examining 66 penetrating colorectal injuries in which the peritoneum was almost always exposed to the normal gastrointestinal microflora it appears that both clindamycin and cephalothin were equally effective in maintaining a relatively low rate of postoperative sepsis when administered early, in combination with an aminoglycoside agent and in addition to intra-operative antibiotic irrigation.",

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AU - Malinin, T. I.

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AB - In examining 66 penetrating colorectal injuries in which the peritoneum was almost always exposed to the normal gastrointestinal microflora it appears that both clindamycin and cephalothin were equally effective in maintaining a relatively low rate of postoperative sepsis when administered early, in combination with an aminoglycoside agent and in addition to intra-operative antibiotic irrigation.

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