Antibiotic prophylaxis in penetrating colorectal injuries: The comparative effectiveness of clindamycin and cephalothin in combination with an aminoglycoside

O. V. Martinez, J. Lancelot Lester, A. Arango, T. I. Malinin

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

In examining 66 penetrating colorectal injuries in which the peritoneum was almost always exposed to the normal gastrointestinal microflora it appears that both clindamycin and cephalothin were equally effective in maintaining a relatively low rate of postoperative sepsis when administered early, in combination with an aminoglycoside agent and in addition to intra-operative antibiotic irrigation.

Original languageEnglish (US)
Pages (from-to)378-383
Number of pages6
JournalAmerican Surgeon
Volume45
Issue number6
StatePublished - Dec 1 1979

ASJC Scopus subject areas

  • Surgery

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