Abstract
Endophthalmitis remains a rare but important cause of visual loss. Prophylaxis strategies are important to reduce rates of endophthalmitis after cataract surgery, intravitreal injection, and other procedures. There is substantial variability between the US and the rest of the world. During cataract surgery, intracameral antibiotics are commonly used in many nations, especially in Europe, but are less commonly used in the US. A randomized clinical trial from the European Society of Cataract and Refractive Surgeons reported an approximately fivefold reduction in endophthalmitis rates associated with intracameral cefuroxime but these results are controversial. There are no randomized clinical trials regarding endophthalmitis associated with intravitreal injection. Topical antibiotics are commonly used in many nations, but are less commonly used in the US. At this time, there is no global consensus and it appears unlikely that additional major clinical trials will conclusively define the optimal endophthalmitis prophylaxis techniques.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 251-256 |
| Number of pages | 6 |
| Journal | Clinical Ophthalmology |
| Volume | 10 |
| DOIs | |
| State | Published - Jan 28 2016 |
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Keywords
- Cataract surgery
- Endophthalmitis
- Intracameral antibiotic
- Intravitreal injection
- Prophylaxis
ASJC Scopus subject areas
- Ophthalmology
Cite this
Antibiotic prophylaxis : Different practice patterns within and outside the United States. / Schwartz, Stephen; Grzybowski, Andrzej; Flynn, Harry W.
In: Clinical Ophthalmology, Vol. 10, 28.01.2016, p. 251-256.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Antibiotic prophylaxis
T2 - Different practice patterns within and outside the United States
AU - Schwartz, Stephen
AU - Grzybowski, Andrzej
AU - Flynn, Harry W
PY - 2016/1/28
Y1 - 2016/1/28
N2 - Endophthalmitis remains a rare but important cause of visual loss. Prophylaxis strategies are important to reduce rates of endophthalmitis after cataract surgery, intravitreal injection, and other procedures. There is substantial variability between the US and the rest of the world. During cataract surgery, intracameral antibiotics are commonly used in many nations, especially in Europe, but are less commonly used in the US. A randomized clinical trial from the European Society of Cataract and Refractive Surgeons reported an approximately fivefold reduction in endophthalmitis rates associated with intracameral cefuroxime but these results are controversial. There are no randomized clinical trials regarding endophthalmitis associated with intravitreal injection. Topical antibiotics are commonly used in many nations, but are less commonly used in the US. At this time, there is no global consensus and it appears unlikely that additional major clinical trials will conclusively define the optimal endophthalmitis prophylaxis techniques.
AB - Endophthalmitis remains a rare but important cause of visual loss. Prophylaxis strategies are important to reduce rates of endophthalmitis after cataract surgery, intravitreal injection, and other procedures. There is substantial variability between the US and the rest of the world. During cataract surgery, intracameral antibiotics are commonly used in many nations, especially in Europe, but are less commonly used in the US. A randomized clinical trial from the European Society of Cataract and Refractive Surgeons reported an approximately fivefold reduction in endophthalmitis rates associated with intracameral cefuroxime but these results are controversial. There are no randomized clinical trials regarding endophthalmitis associated with intravitreal injection. Topical antibiotics are commonly used in many nations, but are less commonly used in the US. At this time, there is no global consensus and it appears unlikely that additional major clinical trials will conclusively define the optimal endophthalmitis prophylaxis techniques.
KW - Cataract surgery
KW - Endophthalmitis
KW - Intracameral antibiotic
KW - Intravitreal injection
KW - Prophylaxis
UR - http://www.scopus.com/inward/record.url?scp=84957111354&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84957111354&partnerID=8YFLogxK
U2 - 10.2147/OPTH.S100429
DO - 10.2147/OPTH.S100429
M3 - Article
AN - SCOPUS:84957111354
VL - 10
SP - 251
EP - 256
JO - Clinical Ophthalmology
JF - Clinical Ophthalmology
SN - 1177-5467
ER -