Anterior-chamber angle and axial length measurements in normal Chinese children

Peiyao Jin, Meili Li, Xiangui He, Lina Lu, Jianfeng Zhu, Ta Chang, Haidong Zou

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7 Scopus citations

Abstract

Purpose: To establish the physiological distribution of anteriorchamber angle parameters and axial length (AL) in a randomly sampled cohort of Chinese children. Patients and Methods: This was a prospective, cross-sectional study on randomly sampled Chinese children ages 7 to 15 years. Complete ophthalmologic examination was carried out on all participants; anterior-segment parameters and ALs were measured using Fourier-domain optical coherence tomography and automated biometers. Associations between the age, the sex, the refractive error, the iris thickness, the AL, and anterior-chamber depth (ACD) and angle measurements were analyzed using multiple correlation and regression tests. The relationship between the AL and other factors was studied by a linear regression analysis. Only the right eye data were analyzed for statistical purpose. Results: A total of 541 children were enrolled in this study. There were no differences in angle parameters between sexes (P>0.05), but boys had a longer AL (P<0.01). The AL increased logarithmically with age in children (P<0.01, R2=0.5552, b=6.18). Although the magnitude of myopia also increased with AL, this association was less robust (P<0.05, R2=0.0917, b=-0.88). A multiple regression test indicated that the age and the ACD were independently associated with the increase in angle width (b=0.37 to 0.50 and 0.51 to 0.60, respectively; P<0.001). Conclusions: All angle measurements increased with age and were positively correlated with the ACD in children 7 to 15 years of age. The AL increased logarithmically with age.

Original languageEnglish (US)
Pages (from-to)692-697
Number of pages6
JournalJournal of Glaucoma
Volume25
Issue number8
DOIs
StatePublished - 2016

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Keywords

  • Anterior-chamber angle
  • Axial length
  • Children
  • Fourier optical coherence tomography

ASJC Scopus subject areas

  • Medicine(all)
  • Ophthalmology

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