Animal models of axon regeneration after spinal cord injury

Do Hun Lee, Jae Lee

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

With advances in genetic and imaging techniques, investigating axon regeneration after spinal cord injury in vivo is becoming more common in the literature. However, there are many issues to consider when using animal models of axon regeneration, including species, strains and injury models. No single particular model suits all types of experiments and each hypothesis being tested requires careful selection of the appropriate animal model. in this review, we describe several commonly-used animal models of axon regeneration in the spinal cord and discuss their advantages and disadvantages.

Original languageEnglish
Pages (from-to)436-444
Number of pages9
JournalNeuroscience Bulletin
Volume29
Issue number4
DOIs
StatePublished - Aug 1 2013

Fingerprint

Spinal Cord Injuries
Axons
Regeneration
Animal Models
Spinal Cord Regeneration
Genetic Techniques
Wounds and Injuries

Keywords

  • contusion
  • injury models
  • pyramidotomy
  • strain differences

ASJC Scopus subject areas

  • Physiology
  • Neuroscience(all)

Cite this

Animal models of axon regeneration after spinal cord injury. / Lee, Do Hun; Lee, Jae.

In: Neuroscience Bulletin, Vol. 29, No. 4, 01.08.2013, p. 436-444.

Research output: Contribution to journalArticle

@article{c9c3e3fd885c4d0a84aaff01300c3dd3,
title = "Animal models of axon regeneration after spinal cord injury",
abstract = "With advances in genetic and imaging techniques, investigating axon regeneration after spinal cord injury in vivo is becoming more common in the literature. However, there are many issues to consider when using animal models of axon regeneration, including species, strains and injury models. No single particular model suits all types of experiments and each hypothesis being tested requires careful selection of the appropriate animal model. in this review, we describe several commonly-used animal models of axon regeneration in the spinal cord and discuss their advantages and disadvantages.",
keywords = "contusion, injury models, pyramidotomy, strain differences",
author = "Lee, {Do Hun} and Jae Lee",
year = "2013",
month = "8",
day = "1",
doi = "10.1007/s12264-013-1365-4",
language = "English",
volume = "29",
pages = "436--444",
journal = "Neuroscience Bulletin",
issn = "1673-7067",
publisher = "Science Press",
number = "4",

}

TY - JOUR

T1 - Animal models of axon regeneration after spinal cord injury

AU - Lee, Do Hun

AU - Lee, Jae

PY - 2013/8/1

Y1 - 2013/8/1

N2 - With advances in genetic and imaging techniques, investigating axon regeneration after spinal cord injury in vivo is becoming more common in the literature. However, there are many issues to consider when using animal models of axon regeneration, including species, strains and injury models. No single particular model suits all types of experiments and each hypothesis being tested requires careful selection of the appropriate animal model. in this review, we describe several commonly-used animal models of axon regeneration in the spinal cord and discuss their advantages and disadvantages.

AB - With advances in genetic and imaging techniques, investigating axon regeneration after spinal cord injury in vivo is becoming more common in the literature. However, there are many issues to consider when using animal models of axon regeneration, including species, strains and injury models. No single particular model suits all types of experiments and each hypothesis being tested requires careful selection of the appropriate animal model. in this review, we describe several commonly-used animal models of axon regeneration in the spinal cord and discuss their advantages and disadvantages.

KW - contusion

KW - injury models

KW - pyramidotomy

KW - strain differences

UR - http://www.scopus.com/inward/record.url?scp=84881157861&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84881157861&partnerID=8YFLogxK

U2 - 10.1007/s12264-013-1365-4

DO - 10.1007/s12264-013-1365-4

M3 - Article

C2 - 23893429

AN - SCOPUS:84881157861

VL - 29

SP - 436

EP - 444

JO - Neuroscience Bulletin

JF - Neuroscience Bulletin

SN - 1673-7067

IS - 4

ER -