The Framingham study established cigarette smoking, elevated serum cholesterol, high systolic blood pressure and advancing age as risk factors for coronary heart disease (Dawber, Meadors, & Moore, 1951). Knowledge about these risk factors alone or in combination, however, still does not predict most new cases of coronary heart disease (CHD) in the United States (Jenkins, 1976). Search for additional risk factors, however, has led to identification by the Western Collaborative Group Study (WCGS) of the Type A coronary-prone behavior pattern as a potential risk factor for CHD (Rosenman, Brand, Jenkins, Friedman, Strauss, & Wurm, 1975). Although the Framingham study and the WCGS demonstrated associations between particular risk factors and CHD, the exact pathophysiologic mechanisms mediating the relationship between any risk factor and CHD are presently unknown.
|Original language||English (US)|
|Title of host publication||Handbook of Psychology and Health|
|Subtitle of host publication||Volume III: Cardiovascular disorders and behavior|
|Publisher||Taylor and Francis|
|Number of pages||38|
|State||Published - Jan 1 2013|
ASJC Scopus subject areas