Angiotensin-converting enzyme in bovine, feline, and human ocular tissues

G. Ferrari-Dileo, J. W. Ryan, E. J. Rockwood, E. B. Davis, D. R. Anderson

Research output: Contribution to journalArticlepeer-review

52 Scopus citations


Angiotensin-converting enzyme was shown to be present in retinal vessels and neural retina of feline, bovine, and human eyes. It was also demonstrated in the other ocular tissues of feline eyes, in especially high concentration in the highly vascular uveal layer. Its role in the physiology of ocular blood flow and neurophysiology is uncertain, especially in the retina where circulating angiotensin and bradykinin are confined to the intravascular space by the blood-retina barrier, and sufficient data are not available to describe these peptides as transmitters or modulator molecules in the retina.

Original languageEnglish (US)
Pages (from-to)876-881
Number of pages6
JournalInvestigative Ophthalmology and Visual Science
Issue number6
StatePublished - 1988
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience


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