Angiogenesis, vasculogenesis, and induction of healing in chronic wounds

Stephen M. Bauer, Richard J. Bauer, Omaida C. Velazquez

Research output: Contribution to journalReview article

149 Scopus citations

Abstract

A key central stage of wound healing requires neovascularization of the wound base granulation tissue. In the adult, neovascularization is now known to occur by both angiogenesis and vasculogenesis. Understanding the biology of these 2 processes offers promising new therapeutic options for patients who suffer from chronic, nonhealing ischemic wounds. The authors review the current literature on the processes of angiogenesis and vasculogenesis and how it relates to wound healing.

Original languageEnglish (US)
Pages (from-to)293-306
Number of pages14
JournalVascular and Endovascular Surgery
Volume39
Issue number4
DOIs
StatePublished - Jul 1 2005
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

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