Angiogenesis in wound healing

Z. J. Liu, O. C. Velazquez

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

Angiogenesis is essential for wound repair. The new blood vessels provide nutrients and oxygen to support cell growth and tissue repair. Neovascularization is a complex multistep process that is dynamic and tightly regulated in a spatial and temporal manner by a variety of signals from soluble factors, extracellular matrix, pericytes, and surrounding stromal cells. Recently, endothelial progenitor cells are known to be involved and, in fact, play a critical role in neovascularization. Understanding the molecular mechanisms that regulate wound angiogenesis may provide novel approaches for treating chronic wounds.

Original languageEnglish (US)
Title of host publicationEncyclopedia of the Eye
PublisherElsevier
Pages99-105
Number of pages7
ISBN (Electronic)9780123742032
ISBN (Print)9780123741981
DOIs
StatePublished - Jan 1 2010

Keywords

  • Angiogenesis
  • Anti-angiogenic factors
  • Blood vessels
  • Endothelial cells
  • Endothelial progenitor cells
  • Extracellular matrix
  • Neovascularization
  • Pericytes
  • Pro-angiogenic factors
  • Stromal cells
  • Vascularization
  • Vasculogenesis
  • Wound healing

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Liu, Z. J., & Velazquez, O. C. (2010). Angiogenesis in wound healing. In Encyclopedia of the Eye (pp. 99-105). Elsevier. https://doi.org/10.1016/B978-0-12-374203-2.00124-X