Androgenetic Alopecia in a Patient with Klinefelter Syndrome: Case Report and Literature Review

Waleed Alsalhi; Antonella Tosti

doi:10.1159/000512224

Androgenetic Alopecia in a Patient with Klinefelter Syndrome: Case Report and Literature Review

Waleed Alsalhi, Antonella Tosti

Dermatology & Cutaneous Surgery

Research output: Contribution to journal › Review article › peer-review

Abstract

Introduction: Klinefelter syndrome (KS) is defined as (a chromosomal disorder in which males have an extra X chromosome). KS presents clinically with signs of androgen deficiency including low testosterone. Androgenetic alopecia (AGA) develops as a response of the hair follicle cells to androgens in individuals with genetic predisposition. Case Presentation: We describe a 17-year-old male patient with KS who developed AGA with a Ludwig pattern. Conclusion: Our patient had a good response to oral minoxidil, finasteride, and low-level light therapy.

Original language	English (US)
Pages (from-to)	135-138
Number of pages	4
Journal	Skin Appendage Disorders
Volume	7
Issue number	2
DOIs	https://doi.org/10.1159/000512224
State	Published - Feb 2021

Keywords

Alopecia
Finasteride
Hair loss
Klinefelter syndrome
Testosterone

ASJC Scopus subject areas

Dermatology

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10.1159/000512224

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title = "Androgenetic Alopecia in a Patient with Klinefelter Syndrome: Case Report and Literature Review",

abstract = "Introduction: Klinefelter syndrome (KS) is defined as (a chromosomal disorder in which males have an extra X chromosome). KS presents clinically with signs of androgen deficiency including low testosterone. Androgenetic alopecia (AGA) develops as a response of the hair follicle cells to androgens in individuals with genetic predisposition. Case Presentation: We describe a 17-year-old male patient with KS who developed AGA with a Ludwig pattern. Conclusion: Our patient had a good response to oral minoxidil, finasteride, and low-level light therapy.",

keywords = "Alopecia, Finasteride, Hair loss, Klinefelter syndrome, Testosterone",

author = "Waleed Alsalhi and Antonella Tosti",

year = "2021",

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language = "English (US)",

volume = "7",

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T1 - Androgenetic Alopecia in a Patient with Klinefelter Syndrome

T2 - Case Report and Literature Review

AU - Alsalhi, Waleed

AU - Tosti, Antonella

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Y1 - 2021/2

N2 - Introduction: Klinefelter syndrome (KS) is defined as (a chromosomal disorder in which males have an extra X chromosome). KS presents clinically with signs of androgen deficiency including low testosterone. Androgenetic alopecia (AGA) develops as a response of the hair follicle cells to androgens in individuals with genetic predisposition. Case Presentation: We describe a 17-year-old male patient with KS who developed AGA with a Ludwig pattern. Conclusion: Our patient had a good response to oral minoxidil, finasteride, and low-level light therapy.

AB - Introduction: Klinefelter syndrome (KS) is defined as (a chromosomal disorder in which males have an extra X chromosome). KS presents clinically with signs of androgen deficiency including low testosterone. Androgenetic alopecia (AGA) develops as a response of the hair follicle cells to androgens in individuals with genetic predisposition. Case Presentation: We describe a 17-year-old male patient with KS who developed AGA with a Ludwig pattern. Conclusion: Our patient had a good response to oral minoxidil, finasteride, and low-level light therapy.

KW - Alopecia

KW - Finasteride

KW - Hair loss

KW - Klinefelter syndrome

KW - Testosterone

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Androgenetic Alopecia in a Patient with Klinefelter Syndrome: Case Report and Literature Review

Abstract

Keywords

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