Androgenetic Alopecia in a Patient with Klinefelter Syndrome: Case Report and Literature Review

Waleed Alsalhi, Antonella Tosti

Research output: Contribution to journalReview articlepeer-review

Abstract

Introduction: Klinefelter syndrome (KS) is defined as (a chromosomal disorder in which males have an extra X chromosome). KS presents clinically with signs of androgen deficiency including low testosterone. Androgenetic alopecia (AGA) develops as a response of the hair follicle cells to androgens in individuals with genetic predisposition. Case Presentation: We describe a 17-year-old male patient with KS who developed AGA with a Ludwig pattern. Conclusion: Our patient had a good response to oral minoxidil, finasteride, and low-level light therapy.

Original languageEnglish (US)
Pages (from-to)135-138
Number of pages4
JournalSkin Appendage Disorders
Volume7
Issue number2
DOIs
StatePublished - Feb 2021
Externally publishedYes

Keywords

  • Alopecia
  • Finasteride
  • Hair loss
  • Klinefelter syndrome
  • Testosterone

ASJC Scopus subject areas

  • Dermatology

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