Anatomic and biomechanical properties of human lumbar dura mater

D. J. Patin, E. C. Eckstein, K. Harum, V. S. Pallares

Research output: Contribution to journalArticlepeer-review

62 Scopus citations

Abstract

Determinants of dural defects subsequent to deliberate or accidental dural puncture include the equipment, techniques, and the inherent anatomic and biomechanical properties of dura mater. These properties were studied in specimens of human and canine lumbar dura mater in an attempt to delineate the structure of the tissue and to characterize its behavior in biomechanical terms. Human dura had a longitudinal orientation on gross appearance, and was confirmed microscopically to be composed of longitudinal lamella of collagen and elastin fibers. Longitudinal tensile strength and stiffness were greater than transverse tensile strength and stiffness, which is consistent with the dura's apparent anatomic structure and functional requirements. Additional biomechanical testing of the dura demonstrated the property of relaxation which is a characteristic of a viscoelastic material. Significant differences were observed between human and canine dural properties, suggesting limited value of this animal model. Integration of these observed anatomic and biochemical properties of the lumbar dura provides a greater understanding of dural puncture and may explain previous and often confusing clinical and experimental findings.

Original languageEnglish (US)
Pages (from-to)535-540
Number of pages6
JournalAnesthesia and analgesia
Volume76
Issue number3
DOIs
StatePublished - Jan 1 1993

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Fingerprint Dive into the research topics of 'Anatomic and biomechanical properties of human lumbar dura mater'. Together they form a unique fingerprint.

Cite this