Abstract
Neuronal firing rate has been the signal of choice for invasive motor brain machine interfaces (BMI). The use of local field potentials (LFP) in BMI experiments may provide additional dendritic information about movement intent and may improve performance. Here we study the time-varying amplitude modulated relationship between local field potentials (LFP) and single unit activity (SUA) in the motor cortex. We record LFP and SUA in the primary motor cortex of rats trained to perform a lever pressing task, and evaluate the correlation between pairs of peri-event time histograms (PETH) and movement evoked local field potentials (mEP) at the same electrode. Three different correlation coefficients were calculated and compared between the neuronal PETH and the magnitude and power of the mEP. Correlation as high as 0.7 for some neurons occurred between the PETH and the mEP magnitude. As expected, the correlations between the single trial LFP and SUV are much lower due to the inherent variability of both signals.
| Original language | English |
|---|---|
| Title of host publication | Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings |
| Pages | 6185-6188 |
| Number of pages | 4 |
| DOIs | |
| State | Published - Dec 1 2006 |
| Externally published | Yes |
| Event | 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 - New York, NY, United States Duration: Aug 30 2006 → Sep 3 2006 |
Other
| Other | 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 |
|---|---|
| Country | United States |
| City | New York, NY |
| Period | 8/30/06 → 9/3/06 |
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ASJC Scopus subject areas
- Bioengineering
Cite this
Analysis of the correlation between local field potentials and neuronal firing rate in the motor cortex. / Yiwen, Wang; Sanchez, Justin C.; Principe, Jose C.; Mitzelfelt, Jeremiah D.; Gunduz, Aysegul.
Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. 2006. p. 6185-6188 4030125.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Analysis of the correlation between local field potentials and neuronal firing rate in the motor cortex
AU - Yiwen, Wang
AU - Sanchez, Justin C.
AU - Principe, Jose C.
AU - Mitzelfelt, Jeremiah D.
AU - Gunduz, Aysegul
PY - 2006/12/1
Y1 - 2006/12/1
N2 - Neuronal firing rate has been the signal of choice for invasive motor brain machine interfaces (BMI). The use of local field potentials (LFP) in BMI experiments may provide additional dendritic information about movement intent and may improve performance. Here we study the time-varying amplitude modulated relationship between local field potentials (LFP) and single unit activity (SUA) in the motor cortex. We record LFP and SUA in the primary motor cortex of rats trained to perform a lever pressing task, and evaluate the correlation between pairs of peri-event time histograms (PETH) and movement evoked local field potentials (mEP) at the same electrode. Three different correlation coefficients were calculated and compared between the neuronal PETH and the magnitude and power of the mEP. Correlation as high as 0.7 for some neurons occurred between the PETH and the mEP magnitude. As expected, the correlations between the single trial LFP and SUV are much lower due to the inherent variability of both signals.
AB - Neuronal firing rate has been the signal of choice for invasive motor brain machine interfaces (BMI). The use of local field potentials (LFP) in BMI experiments may provide additional dendritic information about movement intent and may improve performance. Here we study the time-varying amplitude modulated relationship between local field potentials (LFP) and single unit activity (SUA) in the motor cortex. We record LFP and SUA in the primary motor cortex of rats trained to perform a lever pressing task, and evaluate the correlation between pairs of peri-event time histograms (PETH) and movement evoked local field potentials (mEP) at the same electrode. Three different correlation coefficients were calculated and compared between the neuronal PETH and the magnitude and power of the mEP. Correlation as high as 0.7 for some neurons occurred between the PETH and the mEP magnitude. As expected, the correlations between the single trial LFP and SUV are much lower due to the inherent variability of both signals.
UR - http://www.scopus.com/inward/record.url?scp=34047100409&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34047100409&partnerID=8YFLogxK
U2 - 10.1109/IEMBS.2006.260516
DO - 10.1109/IEMBS.2006.260516
M3 - Conference contribution
AN - SCOPUS:34047100409
SN - 1424400325
SN - 9781424400324
SP - 6185
EP - 6188
BT - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
ER -