Analysis of the correlation between local field potentials and neuronal firing rate in the motor cortex

Wang Yiwen; Justin C. Sanchez; Jose C. Principe; Jeremiah D. Mitzelfelt; Aysegul Gunduz

doi:10.1109/IEMBS.2006.260516

Analysis of the correlation between local field potentials and neuronal firing rate in the motor cortex

Wang Yiwen, Justin C. Sanchez, Jose C. Principe, Jeremiah D. Mitzelfelt, Aysegul Gunduz

Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Neuronal firing rate has been the signal of choice for invasive motor brain machine interfaces (BMI). The use of local field potentials (LFP) in BMI experiments may provide additional dendritic information about movement intent and may improve performance. Here we study the time-varying amplitude modulated relationship between local field potentials (LFP) and single unit activity (SUA) in the motor cortex. We record LFP and SUA in the primary motor cortex of rats trained to perform a lever pressing task, and evaluate the correlation between pairs of peri-event time histograms (PETH) and movement evoked local field potentials (mEP) at the same electrode. Three different correlation coefficients were calculated and compared between the neuronal PETH and the magnitude and power of the mEP. Correlation as high as 0.7 for some neurons occurred between the PETH and the mEP magnitude. As expected, the correlations between the single trial LFP and SUV are much lower due to the inherent variability of both signals.

Original language	English (US)
Title of host publication	28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
Pages	6185-6188
Number of pages	4
DOIs	https://doi.org/10.1109/IEMBS.2006.260516
State	Published - Dec 1 2006
Event	28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 - New York, NY, United States Duration: Aug 30 2006 → Sep 3 2006

Publication series

Name	Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
ISSN (Print)	0589-1019

Other

Other	28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
Country	United States
City	New York, NY
Period	8/30/06 → 9/3/06

ASJC Scopus subject areas

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

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10.1109/IEMBS.2006.260516

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Yiwen, W., Sanchez, J. C., Principe, J. C., Mitzelfelt, J. D., & Gunduz, A. (2006). Analysis of the correlation between local field potentials and neuronal firing rate in the motor cortex. In 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06 (pp. 6185-6188). [4030125] (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings). https://doi.org/10.1109/IEMBS.2006.260516

Analysis of the correlation between local field potentials and neuronal firing rate in the motor cortex. / Yiwen, Wang; Sanchez, Justin C.; Principe, Jose C.; Mitzelfelt, Jeremiah D.; Gunduz, Aysegul.

28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06. 2006. p. 6185-6188 4030125 (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Yiwen, W, Sanchez, JC, Principe, JC, Mitzelfelt, JD & Gunduz, A 2006, Analysis of the correlation between local field potentials and neuronal firing rate in the motor cortex. in 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06., 4030125, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, pp. 6185-6188, 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06, New York, NY, United States, 8/30/06. https://doi.org/10.1109/IEMBS.2006.260516

Yiwen W, Sanchez JC, Principe JC, Mitzelfelt JD, Gunduz A. Analysis of the correlation between local field potentials and neuronal firing rate in the motor cortex. In 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06. 2006. p. 6185-6188. 4030125. (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings). https://doi.org/10.1109/IEMBS.2006.260516

Yiwen, Wang ; Sanchez, Justin C. ; Principe, Jose C. ; Mitzelfelt, Jeremiah D. ; Gunduz, Aysegul. / Analysis of the correlation between local field potentials and neuronal firing rate in the motor cortex. 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06. 2006. pp. 6185-6188 (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings).

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