Analysis of the correlation between local field potentials and neuronal firing rate in the motor cortex.

Yiwen Wang; Justin C. Sanchez; Jose C. Principe; Jeremiah D. Mitzelfelt; Aysegul Gunduz

doi:10.1109/iembs.2006.4398871

Analysis of the correlation between local field potentials and neuronal firing rate in the motor cortex.

Yiwen Wang, Justin C. Sanchez, Jose C. Principe, Jeremiah D. Mitzelfelt, Aysegul Gunduz

Biomedical Engineering

Research output: Contribution to journal › Article

2 Scopus citations

Abstract

Neuronal firing rate has been the signal of choice for invasive motor brain machine interfaces (BMI). The use of local field potentials (LFP) in BMI experiments may provide additional dendritic information about movement intent and may improve performance. Here we study the time-varying amplitude modulated relationship between local field potentials (LFP) and single unit activity (SUA) in the motor cortex. We record LFP and SUA in the primary motor cortex of rats trained to perform a lever pressing task, and evaluate the correlation between pairs of peri-event time histograms (PETH) and movement evoked local field potentials (mEP) at the same electrode. Three different correlation coefficients were calculated and compared between the neuronal PETH and the magnitude and power of the mEP. Correlation as high as 0.7 for some neurons occurred between the PETH and the mEP magnitude. As expected, the correlations between the single trial LFP and SUV are much lower due to the inherent variability of both signals.

Original language	English (US)
Pages (from-to)	6185-6188
Number of pages	4
Journal	Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
DOIs	https://doi.org/10.1109/iembs.2006.4398871
State	Published - 2006

ASJC Scopus subject areas

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

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Wang, Y., Sanchez, J. C., Principe, J. C., Mitzelfelt, J. D., & Gunduz, A. (2006). Analysis of the correlation between local field potentials and neuronal firing rate in the motor cortex. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 6185-6188. https://doi.org/10.1109/iembs.2006.4398871

Analysis of the correlation between local field potentials and neuronal firing rate in the motor cortex. / Wang, Yiwen; Sanchez, Justin C.; Principe, Jose C.; Mitzelfelt, Jeremiah D.; Gunduz, Aysegul.

In: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2006, p. 6185-6188.

Research output: Contribution to journal › Article

Wang, Y, Sanchez, JC, Principe, JC, Mitzelfelt, JD & Gunduz, A 2006, 'Analysis of the correlation between local field potentials and neuronal firing rate in the motor cortex.', Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, pp. 6185-6188. https://doi.org/10.1109/iembs.2006.4398871

Wang Y, Sanchez JC, Principe JC, Mitzelfelt JD, Gunduz A. Analysis of the correlation between local field potentials and neuronal firing rate in the motor cortex. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2006;6185-6188. https://doi.org/10.1109/iembs.2006.4398871

Wang, Yiwen ; Sanchez, Justin C. ; Principe, Jose C. ; Mitzelfelt, Jeremiah D. ; Gunduz, Aysegul. / Analysis of the correlation between local field potentials and neuronal firing rate in the motor cortex. In: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2006 ; pp. 6185-6188.

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