Analysis of histopathological features of endometrioid uterine carcinomas and epidemiologic risk factors

Susan R. Sturgeon, Mark E. Sherman, Robert J. Kurman, Michael L. Berman, Rodrique Mortel, Leo B. Twiggs, Rolland J. Barrett, George D. Wilbanks, Louise A. Brinton

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

A large case-control study was performed to determine whether risk factors for endometrioid carcinoma, the most common type of endometrial cancer, vary according to the histological features of the tumor. Study subjects consisted of 328 women with newly diagnosed endometrioid adenocarcinoma and 320 population-based control subjects. Variables studied included age at menarche, menopausal estrogen use, weight, parity, cigarette smoking, and oral contraceptive use. The risk factor profile for endometrioid carcinomas with and without squamous differentiation was very similar. No striking differences in risk factors were observed between endometrioid cancers with and without adjacent endometrial hyperplasia. Finally, none of the risk factors varied substantially between early-stage and late-stage tumors or low-grade and high-grade tumors. In summary, this study indicates that risk factors for endometrioid carcinomas are not related to the morphological features of the tumor.

Original languageEnglish
Pages (from-to)231-235
Number of pages5
JournalCancer Epidemiology Biomarkers and Prevention
Volume7
Issue number3
StatePublished - Mar 1 1998
Externally publishedYes

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Epidemiologic Factors
Endometrioid Carcinoma
Neoplasms
Endometrial Hyperplasia
Menarche
Population Control
Endometrial Neoplasms
Oral Contraceptives
Parity
Case-Control Studies
Estrogens
Smoking
Weights and Measures

ASJC Scopus subject areas

  • Epidemiology
  • Oncology

Cite this

Sturgeon, S. R., Sherman, M. E., Kurman, R. J., Berman, M. L., Mortel, R., Twiggs, L. B., ... Brinton, L. A. (1998). Analysis of histopathological features of endometrioid uterine carcinomas and epidemiologic risk factors. Cancer Epidemiology Biomarkers and Prevention, 7(3), 231-235.

Analysis of histopathological features of endometrioid uterine carcinomas and epidemiologic risk factors. / Sturgeon, Susan R.; Sherman, Mark E.; Kurman, Robert J.; Berman, Michael L.; Mortel, Rodrique; Twiggs, Leo B.; Barrett, Rolland J.; Wilbanks, George D.; Brinton, Louise A.

In: Cancer Epidemiology Biomarkers and Prevention, Vol. 7, No. 3, 01.03.1998, p. 231-235.

Research output: Contribution to journalArticle

Sturgeon, SR, Sherman, ME, Kurman, RJ, Berman, ML, Mortel, R, Twiggs, LB, Barrett, RJ, Wilbanks, GD & Brinton, LA 1998, 'Analysis of histopathological features of endometrioid uterine carcinomas and epidemiologic risk factors', Cancer Epidemiology Biomarkers and Prevention, vol. 7, no. 3, pp. 231-235.
Sturgeon SR, Sherman ME, Kurman RJ, Berman ML, Mortel R, Twiggs LB et al. Analysis of histopathological features of endometrioid uterine carcinomas and epidemiologic risk factors. Cancer Epidemiology Biomarkers and Prevention. 1998 Mar 1;7(3):231-235.
Sturgeon, Susan R. ; Sherman, Mark E. ; Kurman, Robert J. ; Berman, Michael L. ; Mortel, Rodrique ; Twiggs, Leo B. ; Barrett, Rolland J. ; Wilbanks, George D. ; Brinton, Louise A. / Analysis of histopathological features of endometrioid uterine carcinomas and epidemiologic risk factors. In: Cancer Epidemiology Biomarkers and Prevention. 1998 ; Vol. 7, No. 3. pp. 231-235.
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