An operational definition of epigenetics

Shelley L. Berger, Tony Kouzarides, Ramin Shiekhattar, Ali Shilatifard

Research output: Contribution to journalArticle

896 Scopus citations

Abstract

A recent meeting (December 2008) regarding chromatinbased epigenetics was hosted by the Banbury Conference Center and Cold Spring Harbor Laboratory. The intent was to discuss aspects of epigenetic control of genomic function, and to arrive at a consensus definition of "epigenetics" to be considered by the broader community. It was evident that multiple mechanistic steps lead to the stable heritance of the epigenetic phenotype. Below we provide our view and interpretation of the proceedings at the meeting.

Original languageEnglish (US)
Pages (from-to)781-783
Number of pages3
JournalGenes and Development
Volume23
Issue number7
DOIs
StatePublished - Apr 1 2009
Externally publishedYes

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Keywords

  • DNA methylation
  • Histone modification
  • Histone variant
  • Noncoding RNA

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology
  • Medicine(all)

Cite this

Berger, S. L., Kouzarides, T., Shiekhattar, R., & Shilatifard, A. (2009). An operational definition of epigenetics. Genes and Development, 23(7), 781-783. https://doi.org/10.1101/gad.1787609