Abstract
The US and Queensland populations both demonstrate an increased risk of secondary malignancies following the diagnosis of Merkel cell carcinoma (MCC). A recent Queensland study failed to demonstrate a significantly increased risk of developing non-Hodgkin lymphoma (NHL) or chronic lymphocytic leukaemia (CLL) in these patients. In contrast, using the US Surveillance, Epidemiology, and End Results database, we demonstrate there is an increased risk in CLL and NHL following the diagnosis of MCC in the USA. We hypothesise that this difference may be a result of a differing pathogenesis.
| Original language | English (US) |
|---|---|
| Journal | Australasian Journal of Dermatology |
| DOIs | |
| State | Accepted/In press - 2015 |
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Keywords
- CLL
- Merkel cell carcinoma
- Merkel cell polyomavirus
- Non-Hodgkin lymphoma
- SEER
ASJC Scopus subject areas
- Dermatology
Cite this
An increased risk of non-Hodgkin lymphoma and chronic lymphocytic leukemia in US patients with Merkel cell carcinoma versus Australian patients : A clinical clue to a different mechanism of pathogenesis? / Bloom, Romi; Amber, Kyle T.; Nouri, Keyvan.
In: Australasian Journal of Dermatology, 2015.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - An increased risk of non-Hodgkin lymphoma and chronic lymphocytic leukemia in US patients with Merkel cell carcinoma versus Australian patients
T2 - A clinical clue to a different mechanism of pathogenesis?
AU - Bloom, Romi
AU - Amber, Kyle T.
AU - Nouri, Keyvan
PY - 2015
Y1 - 2015
N2 - The US and Queensland populations both demonstrate an increased risk of secondary malignancies following the diagnosis of Merkel cell carcinoma (MCC). A recent Queensland study failed to demonstrate a significantly increased risk of developing non-Hodgkin lymphoma (NHL) or chronic lymphocytic leukaemia (CLL) in these patients. In contrast, using the US Surveillance, Epidemiology, and End Results database, we demonstrate there is an increased risk in CLL and NHL following the diagnosis of MCC in the USA. We hypothesise that this difference may be a result of a differing pathogenesis.
AB - The US and Queensland populations both demonstrate an increased risk of secondary malignancies following the diagnosis of Merkel cell carcinoma (MCC). A recent Queensland study failed to demonstrate a significantly increased risk of developing non-Hodgkin lymphoma (NHL) or chronic lymphocytic leukaemia (CLL) in these patients. In contrast, using the US Surveillance, Epidemiology, and End Results database, we demonstrate there is an increased risk in CLL and NHL following the diagnosis of MCC in the USA. We hypothesise that this difference may be a result of a differing pathogenesis.
KW - CLL
KW - Merkel cell carcinoma
KW - Merkel cell polyomavirus
KW - Non-Hodgkin lymphoma
KW - SEER
UR - http://www.scopus.com/inward/record.url?scp=84925264909&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84925264909&partnerID=8YFLogxK
U2 - 10.1111/ajd.12325
DO - 10.1111/ajd.12325
M3 - Article
C2 - 25801041
AN - SCOPUS:84925264909
JO - Australasian Journal of Dermatology
JF - Australasian Journal of Dermatology
SN - 0004-8380
ER -