An exploration of common dopaminergic variants and behavior problems in siblings at high risk for autism spectrum disorder

Devon N. Gangi; Lauren V. Usher; Daniel S. Messinger

doi:10.1016/j.infbeh.2017.10.002

An exploration of common dopaminergic variants and behavior problems in siblings at high risk for autism spectrum disorder

Devon N. Gangi, Lauren V. Usher, Daniel S. Messinger

Psychology

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Younger siblings of children with ASD often exhibit elevated internalizing and externalizing problems. We investigated common dopaminergic variants (DRD4 and DRD2) in relation to behavior problems at 36 months. Genotypes linked to less efficient dopaminergic functioning were associated with higher internalizing problems in high-risk siblings.

Original language	English (US)
Pages (from-to)	267-271
Number of pages	5
Journal	Infant Behavior and Development
Volume	49
DOIs	https://doi.org/10.1016/j.infbeh.2017.10.002
State	Published - Nov 2017

Keywords

Behavior problems
Dopamine
High-risk siblings

ASJC Scopus subject areas

Developmental and Educational Psychology

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10.1016/j.infbeh.2017.10.002

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title = "An exploration of common dopaminergic variants and behavior problems in siblings at high risk for autism spectrum disorder",

abstract = "Younger siblings of children with ASD often exhibit elevated internalizing and externalizing problems. We investigated common dopaminergic variants (DRD4 and DRD2) in relation to behavior problems at 36 months. Genotypes linked to less efficient dopaminergic functioning were associated with higher internalizing problems in high-risk siblings.",

keywords = "Behavior problems, Dopamine, High-risk siblings",

author = "Gangi, {Devon N.} and Usher, {Lauren V.} and Messinger, {Daniel S.}",

note = "Funding Information: This research was supported by the National Institute of Mental Health (T32 MH073124 ), National Institute of Child Health and Human Development ( T32 HD07489 ), National Institutes of Health ( R01 HD047417 and R01 HD057284 ), National Institute of General Medical Sciences ( R01 GM105004 ), and Autism Speaks . ",

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AU - Gangi, Devon N.

AU - Usher, Lauren V.

AU - Messinger, Daniel S.

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