An event-related potential study on the effects of cannabis on emotion processing

Lucy J. Troup, Stephanie Bastidas, Maia T. Nguyen, Jeremy A. Andrzejewski, Matthew Bowers, Jason Nomi

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9 Scopus citations

Abstract

The effect of cannabis on emotional processing was investigated using event-related potential paradigms (ERPs). ERPs associated with emotional processing of cannabis users, and non-using controls, were recorded and compared during an implicit and explicit emotional expression recognition and empathy task. Comparisons in P3 component mean amplitudes were made between cannabis users and controls. Results showed a significant decrease in the P3 amplitude in cannabis users compared to controls. Specifically, cannabis users showed reduced P3 amplitudes for implicit compared to explicit processing over centroparietal sites which reversed, and was enhanced, at fronto-central sites. Cannabis users also showed a decreased P3 to happy faces, with an increase to angry faces, compared to controls. These effects appear to increase with those participants that self-reported the highest levels of cannabis consumption. Those cannabis users with the greatest consumption rates showed the largest P3 deficits for explicit processing and negative emotions. These data suggest that there is a complex relationship between cannabis consumption and emotion processing that appears to be modulated by attention.

Original languageEnglish (US)
Article numbere0149764
JournalPLoS One
Volume11
Issue number2
DOIs
StatePublished - Feb 1 2016

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ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Troup, L. J., Bastidas, S., Nguyen, M. T., Andrzejewski, J. A., Bowers, M., & Nomi, J. (2016). An event-related potential study on the effects of cannabis on emotion processing. PLoS One, 11(2), [e0149764]. https://doi.org/10.1371/journal.pone.0149764