Abstract
Intervertebral disk (IVD) is the largest avascular structure in human body, consisting of three types of charged hydrated soft tissues. Its mechanical behavior is nonlinear and anisotropic, due mainly to nonlinear interactions among different constituents within tissues. In this study, a more realistic anisotropic multiphysics model was developed based on the continuum mixture theory and employed to characterize the couplings of multiple physical fields in the IVD. Numerical simulations demonstrate that this model is capable of systematically predicting the mechanical and electrochemical signals within the disk under various loading conditions, which is essential in understanding the mechanobiology of IVD.
| Original language | English (US) |
|---|---|
| Article number | 021001 |
| Journal | Journal of Applied Mechanics, Transactions ASME |
| Volume | 83 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 1 2016 |
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Keywords
- anisotropic diffusivity
- anisotropic permeability
- biomechanics
- mixture theory
- multiphase
ASJC Scopus subject areas
- Mechanical Engineering
- Mechanics of Materials
- Condensed Matter Physics
Cite this
An Anisotropic Multiphysics Model for Intervertebral Disk. / Gao, Xin; Zhu, Qiaoqiao; Gu, Weiyong.
In: Journal of Applied Mechanics, Transactions ASME, Vol. 83, No. 2, 021001, 01.02.2016.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - An Anisotropic Multiphysics Model for Intervertebral Disk
AU - Gao, Xin
AU - Zhu, Qiaoqiao
AU - Gu, Weiyong
PY - 2016/2/1
Y1 - 2016/2/1
N2 - Intervertebral disk (IVD) is the largest avascular structure in human body, consisting of three types of charged hydrated soft tissues. Its mechanical behavior is nonlinear and anisotropic, due mainly to nonlinear interactions among different constituents within tissues. In this study, a more realistic anisotropic multiphysics model was developed based on the continuum mixture theory and employed to characterize the couplings of multiple physical fields in the IVD. Numerical simulations demonstrate that this model is capable of systematically predicting the mechanical and electrochemical signals within the disk under various loading conditions, which is essential in understanding the mechanobiology of IVD.
AB - Intervertebral disk (IVD) is the largest avascular structure in human body, consisting of three types of charged hydrated soft tissues. Its mechanical behavior is nonlinear and anisotropic, due mainly to nonlinear interactions among different constituents within tissues. In this study, a more realistic anisotropic multiphysics model was developed based on the continuum mixture theory and employed to characterize the couplings of multiple physical fields in the IVD. Numerical simulations demonstrate that this model is capable of systematically predicting the mechanical and electrochemical signals within the disk under various loading conditions, which is essential in understanding the mechanobiology of IVD.
KW - anisotropic diffusivity
KW - anisotropic permeability
KW - biomechanics
KW - mixture theory
KW - multiphase
UR - http://www.scopus.com/inward/record.url?scp=84946882137&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84946882137&partnerID=8YFLogxK
U2 - 10.1115/1.4031793
DO - 10.1115/1.4031793
M3 - Article
AN - SCOPUS:84946882137
VL - 83
JO - Journal of Applied Mechanics, Transactions ASME
JF - Journal of Applied Mechanics, Transactions ASME
SN - 0021-8936
IS - 2
M1 - 021001
ER -