Abstract
Intervertebral disk (IVD) is the largest avascular structure in human body, consisting of three types of charged hydrated soft tissues. Its mechanical behavior is nonlinear and anisotropic, due mainly to nonlinear interactions among different constituents within tissues. In this study, a more realistic anisotropic multiphysics model was developed based on the continuum mixture theory and employed to characterize the couplings of multiple physical fields in the IVD. Numerical simulations demonstrate that this model is capable of systematically predicting the mechanical and electrochemical signals within the disk under various loading conditions, which is essential in understanding the mechanobiology of IVD.
| Original language | English (US) |
|---|---|
| Article number | 021001 |
| Journal | Journal of Applied Mechanics, Transactions ASME |
| Volume | 83 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 1 2016 |
Keywords
- anisotropic diffusivity
- anisotropic permeability
- biomechanics
- mixture theory
- multiphase
ASJC Scopus subject areas
- Mechanical Engineering
- Mechanics of Materials
- Condensed Matter Physics
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Cite this
Gao, X., Zhu, Q., & Gu, W. (2016). An Anisotropic Multiphysics Model for Intervertebral Disk. Journal of Applied Mechanics, Transactions ASME, 83(2), [021001]. https://doi.org/10.1115/1.4031793