Abstract
By a mixed rosette technique, a small population of lymphocytes possessing both the T-cell characteristic of spontaneous rosette formation with sheep erythrocytes and B-cell membrane receptors for IgG or complement was found in the peripheral blood of all four patients with X-linked infantile agammaglobulinemia. The relative proportions of these lymphocytes, tentatively called D-lymphocytes, are comparable to those of healthy persons. Both the surface receptor features of D-lymphocytes and the presence of these cells in patients lacking B-lymphocytes suggest that these lymphocytes may be independent of the B-lymphocyte population.
Original language | English (US) |
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Pages (from-to) | 141-148 |
Number of pages | 8 |
Journal | Clinical Immunology and Immunopathology |
Volume | 6 |
Issue number | 2 |
DOIs | |
State | Published - Sep 1976 |
Externally published | Yes |
ASJC Scopus subject areas
- Immunology and Allergy
- Pathology and Forensic Medicine
- Immunology