An analysis of characteristics of subjects examined for incretin effects on pancreatic pathology

Evis Harja, Jonathan Lord, Jay S Skyler

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

A recent autopsy analysis asserted that incretin drugs have the potential of increasing the risk for pancreatic cancer and for pancreatic neuroendocrine tumors. We examined the Network for Pancreatic Organ Donors with Diabetes (nPOD) database from which that analysis was derived. Our findings raise important questions about the comparability of the two groups of diabetes patients used for the analysis. Our review of the data available on the nPOD Web site and our reading of the earlier article lead us to the conclusion that the data, and the implications of the data, as expressed by the authors of the autopsy analysis are vastly overstated and are a misrepresentation of the information available.

Original languageEnglish
Pages (from-to)609-618
Number of pages10
JournalDiabetes Technology and Therapeutics
Volume15
Issue number8
DOIs
StatePublished - Aug 1 2013

Fingerprint

Incretins
Autopsy
Tissue Donors
Pathology
Neuroendocrine Tumors
Pancreatic Neoplasms
Reading
Databases
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Medical Laboratory Technology

Cite this

An analysis of characteristics of subjects examined for incretin effects on pancreatic pathology. / Harja, Evis; Lord, Jonathan; Skyler, Jay S.

In: Diabetes Technology and Therapeutics, Vol. 15, No. 8, 01.08.2013, p. 609-618.

Research output: Contribution to journalArticle

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