An alternative approach to amyloid fibrils morphology: CdSe/ZnS quantum dots labelled β-amyloid peptide fragments Aβ (31-35), Aβ (1-40) and Aβ (1-42)

Xiaojun Ji; David Naistat; Changqing Li; Jhony Orbulescu; Roger M. Leblanc

doi:10.1016/j.colsurfb.2006.02.010

An alternative approach to amyloid fibrils morphology: CdSe/ZnS quantum dots labelled β-amyloid peptide fragments Aβ (31-35), Aβ (1-40) and Aβ (1-42)

Xiaojun Ji, David Naistat, Changqing Li, Jhony Orbulescu, Roger M. Leblanc

Chemistry

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Aβ (31-35) peptide and control peptides as well as full length Aβ (1-40) and Aβ (1-42) peptides were labelled with luminescent CdSe/ZnS quantum dots (QDs) to observe the morphology of amyloid fibers. A comparison was made between QDs and an organic dye, namely Dansyl group, which showed that the QDs present a much better contrast for imaging than the organic dye.

Original language	English (US)
Pages (from-to)	104-111
Number of pages	8
Journal	Colloids and Surfaces B: Biointerfaces
Volume	50
Issue number	2
DOIs	https://doi.org/10.1016/j.colsurfb.2006.02.010
State	Published - Jul 1 2006

Keywords

β-Amyloid peptide
Fluorescence imaging
Quantum dots

ASJC Scopus subject areas

Biotechnology
Colloid and Surface Chemistry
Physical and Theoretical Chemistry
Surfaces and Interfaces

Access to Document

10.1016/j.colsurfb.2006.02.010

Fingerprint Dive into the research topics of 'An alternative approach to amyloid fibrils morphology: CdSe/ZnS quantum dots labelled β-amyloid peptide fragments Aβ (31-35), Aβ (1-40) and Aβ (1-42)'. Together they form a unique fingerprint.

Cite this

An alternative approach to amyloid fibrils morphology : CdSe/ZnS quantum dots labelled β-amyloid peptide fragments Aβ (31-35), Aβ (1-40) and Aβ (1-42). / Ji, Xiaojun; Naistat, David; Li, Changqing; Orbulescu, Jhony; Leblanc, Roger M.

In: Colloids and Surfaces B: Biointerfaces, Vol. 50, No. 2, 01.07.2006, p. 104-111.

Research output: Contribution to journal › Article › peer-review

@article{31e602df255f4ca5aa41b540809d5878,

title = "An alternative approach to amyloid fibrils morphology: CdSe/ZnS quantum dots labelled β-amyloid peptide fragments Aβ (31-35), Aβ (1-40) and Aβ (1-42)",

abstract = "Aβ (31-35) peptide and control peptides as well as full length Aβ (1-40) and Aβ (1-42) peptides were labelled with luminescent CdSe/ZnS quantum dots (QDs) to observe the morphology of amyloid fibers. A comparison was made between QDs and an organic dye, namely Dansyl group, which showed that the QDs present a much better contrast for imaging than the organic dye.",

keywords = "β-Amyloid peptide, Fluorescence imaging, Quantum dots",

author = "Xiaojun Ji and David Naistat and Changqing Li and Jhony Orbulescu and Leblanc, {Roger M.}",

note = "Funding Information: We thank Dr. David B. Teplow for his generous gifts of Aβ (1–40) and Aβ (1–42) peptides. This research was supported by the National Science Foundation (USA, CHE-0091390).",

year = "2006",

month = jul,

day = "1",

doi = "10.1016/j.colsurfb.2006.02.010",

language = "English (US)",

volume = "50",

pages = "104--111",

journal = "Colloids and Surfaces B: Biointerfaces",

issn = "0927-7765",

publisher = "Elsevier",

number = "2",

}

TY - JOUR

T1 - An alternative approach to amyloid fibrils morphology

T2 - CdSe/ZnS quantum dots labelled β-amyloid peptide fragments Aβ (31-35), Aβ (1-40) and Aβ (1-42)

AU - Ji, Xiaojun

AU - Naistat, David

AU - Li, Changqing

AU - Orbulescu, Jhony

AU - Leblanc, Roger M.

N1 - Funding Information: We thank Dr. David B. Teplow for his generous gifts of Aβ (1–40) and Aβ (1–42) peptides. This research was supported by the National Science Foundation (USA, CHE-0091390).

PY - 2006/7/1

Y1 - 2006/7/1

N2 - Aβ (31-35) peptide and control peptides as well as full length Aβ (1-40) and Aβ (1-42) peptides were labelled with luminescent CdSe/ZnS quantum dots (QDs) to observe the morphology of amyloid fibers. A comparison was made between QDs and an organic dye, namely Dansyl group, which showed that the QDs present a much better contrast for imaging than the organic dye.

AB - Aβ (31-35) peptide and control peptides as well as full length Aβ (1-40) and Aβ (1-42) peptides were labelled with luminescent CdSe/ZnS quantum dots (QDs) to observe the morphology of amyloid fibers. A comparison was made between QDs and an organic dye, namely Dansyl group, which showed that the QDs present a much better contrast for imaging than the organic dye.

KW - β-Amyloid peptide

KW - Fluorescence imaging

KW - Quantum dots

UR - http://www.scopus.com/inward/record.url?scp=33745430441&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33745430441&partnerID=8YFLogxK

U2 - 10.1016/j.colsurfb.2006.02.010

DO - 10.1016/j.colsurfb.2006.02.010

M3 - Article

C2 - 16766161

AN - SCOPUS:33745430441

VL - 50

SP - 104

EP - 111

JO - Colloids and Surfaces B: Biointerfaces

JF - Colloids and Surfaces B: Biointerfaces

SN - 0927-7765

IS - 2

ER -

An alternative approach to amyloid fibrils morphology: CdSe/ZnS quantum dots labelled β-amyloid peptide fragments Aβ (31-35), Aβ (1-40) and Aβ (1-42)

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this