An alternative approach to amyloid fibrils morphology: CdSe/ZnS quantum dots labelled β-amyloid peptide fragments Aβ (31-35), Aβ (1-40) and Aβ (1-42)

Xiaojun Ji, David Naistat, Changqing Li, Jhony Orbulescu, Roger Leblanc

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Aβ (31-35) peptide and control peptides as well as full length Aβ (1-40) and Aβ (1-42) peptides were labelled with luminescent CdSe/ZnS quantum dots (QDs) to observe the morphology of amyloid fibers. A comparison was made between QDs and an organic dye, namely Dansyl group, which showed that the QDs present a much better contrast for imaging than the organic dye.

Original languageEnglish
Pages (from-to)104-111
Number of pages8
JournalColloids and Surfaces B: Biointerfaces
Volume50
Issue number2
DOIs
StatePublished - Jul 1 2006

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Quantum Dots
Peptide Fragments
Amyloid
Peptides
Semiconductor quantum dots
peptides
quantum dots
fragments
Coloring Agents
Dyes
dyes
Imaging techniques
fibers
Fibers

Keywords

  • β-Amyloid peptide
  • Fluorescence imaging
  • Quantum dots

ASJC Scopus subject areas

  • Biotechnology
  • Colloid and Surface Chemistry
  • Physical and Theoretical Chemistry
  • Surfaces and Interfaces

Cite this

An alternative approach to amyloid fibrils morphology : CdSe/ZnS quantum dots labelled β-amyloid peptide fragments Aβ (31-35), Aβ (1-40) and Aβ (1-42). / Ji, Xiaojun; Naistat, David; Li, Changqing; Orbulescu, Jhony; Leblanc, Roger.

In: Colloids and Surfaces B: Biointerfaces, Vol. 50, No. 2, 01.07.2006, p. 104-111.

Research output: Contribution to journalArticle

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