An alternative approach to amyloid fibrils morphology: CdSe/ZnS quantum dots labelled β-amyloid peptide fragments Aβ (31-35), Aβ (1-40) and Aβ (1-42)

Xiaojun Ji; David Naistat; Changqing Li; Jhony Orbulescu; Roger M. Leblanc

doi:10.1016/j.colsurfb.2006.02.010

An alternative approach to amyloid fibrils morphology: CdSe/ZnS quantum dots labelled β-amyloid peptide fragments Aβ (31-35), Aβ (1-40) and Aβ (1-42)

Xiaojun Ji, David Naistat, Changqing Li, Jhony Orbulescu, Roger M. Leblanc

Chemistry

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

Aβ (31-35) peptide and control peptides as well as full length Aβ (1-40) and Aβ (1-42) peptides were labelled with luminescent CdSe/ZnS quantum dots (QDs) to observe the morphology of amyloid fibers. A comparison was made between QDs and an organic dye, namely Dansyl group, which showed that the QDs present a much better contrast for imaging than the organic dye.

Original language	English (US)
Pages (from-to)	104-111
Number of pages	8
Journal	Colloids and Surfaces B: Biointerfaces
Volume	50
Issue number	2
DOIs	https://doi.org/10.1016/j.colsurfb.2006.02.010
State	Published - Jul 1 2006

Keywords

β-Amyloid peptide
Fluorescence imaging
Quantum dots

ASJC Scopus subject areas

Biotechnology
Colloid and Surface Chemistry
Physical and Theoretical Chemistry
Surfaces and Interfaces

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10.1016/j.colsurfb.2006.02.010

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An alternative approach to amyloid fibrils morphology : CdSe/ZnS quantum dots labelled β-amyloid peptide fragments Aβ (31-35), Aβ (1-40) and Aβ (1-42). / Ji, Xiaojun; Naistat, David; Li, Changqing; Orbulescu, Jhony; Leblanc, Roger M.

In: Colloids and Surfaces B: Biointerfaces, Vol. 50, No. 2, 01.07.2006, p. 104-111.

Research output: Contribution to journal › Article › peer-review

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abstract = "Aβ (31-35) peptide and control peptides as well as full length Aβ (1-40) and Aβ (1-42) peptides were labelled with luminescent CdSe/ZnS quantum dots (QDs) to observe the morphology of amyloid fibers. A comparison was made between QDs and an organic dye, namely Dansyl group, which showed that the QDs present a much better contrast for imaging than the organic dye.",

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author = "Xiaojun Ji and David Naistat and Changqing Li and Jhony Orbulescu and Leblanc, {Roger M.}",

note = "Funding Information: We thank Dr. David B. Teplow for his generous gifts of Aβ (1–40) and Aβ (1–42) peptides. This research was supported by the National Science Foundation (USA, CHE-0091390).",

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AU - Li, Changqing

AU - Orbulescu, Jhony

AU - Leblanc, Roger M.

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An alternative approach to amyloid fibrils morphology: CdSe/ZnS quantum dots labelled β-amyloid peptide fragments Aβ (31-35), Aβ (1-40) and Aβ (1-42)

Abstract

Keywords

ASJC Scopus subject areas

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