An acquired robertsonian translocation dic(14;14)(p11;p11) in a patient with a myelodysplastic syndrome following treatment of multiple myeloma

Yao-Shan Fan, Maria R. Baer, Sheila N. Jani Sait, Paola Dal Cin, Theodore C. Prentice, Harvey D. Preisler, Avery A. Sandberg

Research output: Contribution to journalArticle

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Abstract

Acquired Robertsonian translocations are considered to be very rare chromosome changes in human malignancy, and only three cases have been described. We report a dic(14;14)(p11;p11) in a patient with myelodysplastic syndromes (MDS) following treatment for multiple myeloma. This patient also had other complex chromosomal abnormalities. The pattern of karyotype evolution in this patient was established by a series of cytogenetic studies. The relationship of the complex chromosomal changes to MDS following treatment for multiple myeloma is discussed.

Original languageEnglish
Pages (from-to)133-137
Number of pages5
JournalCancer Genetics and Cytogenetics
Volume30
Issue number1
DOIs
StatePublished - Jan 1 1988
Externally publishedYes

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Myelodysplastic Syndromes
Multiple Myeloma
Karyotype
Cytogenetics
Chromosome Aberrations
Therapeutics
Chromosomes
Neoplasms

ASJC Scopus subject areas

  • Cancer Research
  • Genetics
  • Molecular Biology

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An acquired robertsonian translocation dic(14;14)(p11;p11) in a patient with a myelodysplastic syndrome following treatment of multiple myeloma. / Fan, Yao-Shan; Baer, Maria R.; Jani Sait, Sheila N.; Cin, Paola Dal; Prentice, Theodore C.; Preisler, Harvey D.; Sandberg, Avery A.

In: Cancer Genetics and Cytogenetics, Vol. 30, No. 1, 01.01.1988, p. 133-137.

Research output: Contribution to journalArticle

Fan, Yao-Shan ; Baer, Maria R. ; Jani Sait, Sheila N. ; Cin, Paola Dal ; Prentice, Theodore C. ; Preisler, Harvey D. ; Sandberg, Avery A. / An acquired robertsonian translocation dic(14;14)(p11;p11) in a patient with a myelodysplastic syndrome following treatment of multiple myeloma. In: Cancer Genetics and Cytogenetics. 1988 ; Vol. 30, No. 1. pp. 133-137.
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