An acquired robertsonian translocation dic(14;14)(p11;p11) in a patient with a myelodysplastic syndrome following treatment of multiple myeloma

Yao Shan Fan; Maria R. Baer; Sheila N. Jani Sait; Paola Dal Cin; Theodore C. Prentice; Harvey D. Preisler; Avery A. Sandberg

doi:10.1016/0165-4608(88)90101-X

An acquired robertsonian translocation dic(14;14)(p11;p11) in a patient with a myelodysplastic syndrome following treatment of multiple myeloma

Yao Shan Fan, Maria R. Baer, Sheila N. Jani Sait, Paola Dal Cin, Theodore C. Prentice, Harvey D. Preisler, Avery A. Sandberg

Research output: Contribution to journal › Article

8 Scopus citations

Abstract

Acquired Robertsonian translocations are considered to be very rare chromosome changes in human malignancy, and only three cases have been described. We report a dic(14;14)(p11;p11) in a patient with myelodysplastic syndromes (MDS) following treatment for multiple myeloma. This patient also had other complex chromosomal abnormalities. The pattern of karyotype evolution in this patient was established by a series of cytogenetic studies. The relationship of the complex chromosomal changes to MDS following treatment for multiple myeloma is discussed.

Original language	English (US)
Pages (from-to)	133-137
Number of pages	5
Journal	Cancer Genetics and Cytogenetics
Volume	30
Issue number	1
DOIs	https://doi.org/10.1016/0165-4608(88)90101-X
State	Published - Jan 1988
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Genetics
Cancer Research

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Fan, Y. S., Baer, M. R., Jani Sait, S. N., Cin, P. D., Prentice, T. C., Preisler, H. D., & Sandberg, A. A. (1988). An acquired robertsonian translocation dic(14;14)(p11;p11) in a patient with a myelodysplastic syndrome following treatment of multiple myeloma. Cancer Genetics and Cytogenetics, 30(1), 133-137. https://doi.org/10.1016/0165-4608(88)90101-X

An acquired robertsonian translocation dic(14;14)(p11;p11) in a patient with a myelodysplastic syndrome following treatment of multiple myeloma. / Fan, Yao Shan; Baer, Maria R.; Jani Sait, Sheila N.; Cin, Paola Dal; Prentice, Theodore C.; Preisler, Harvey D.; Sandberg, Avery A.

In: Cancer Genetics and Cytogenetics, Vol. 30, No. 1, 01.1988, p. 133-137.

Research output: Contribution to journal › Article

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abstract = "Acquired Robertsonian translocations are considered to be very rare chromosome changes in human malignancy, and only three cases have been described. We report a dic(14;14)(p11;p11) in a patient with myelodysplastic syndromes (MDS) following treatment for multiple myeloma. This patient also had other complex chromosomal abnormalities. The pattern of karyotype evolution in this patient was established by a series of cytogenetic studies. The relationship of the complex chromosomal changes to MDS following treatment for multiple myeloma is discussed.",

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