An absence of structural changes in the proximal femur with osteoporosis

Satoru Saitoh, Yukio Nakatsuchi, Loren Latta, Edward Milne

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


The hypothesis that osteoporosis occurs not as a preferential loss of the tensile trabeculae but as a general loss of bone was tested by using bone mineral densitometry and an indention test on dissected proximal femora. As osteoporosis advanced a significantly correlated decrease was found in both bone mineral density and mechanical properties between the principal compressive and tensile trabeculae. The decrease correlated with a decrease in the Singh index. These findings led to the conclusion that a sequential bone loss from the tensile trabeculae to the compressive ones did not occur as Singh reported, but instead a generalized loss of bone mineral in both the tensile and compressive trabeculae supervened. The structural changes, on which the grading system by Singh was based, were not observed in the proximal femur affected by osteoporosis.

Original languageEnglish (US)
Pages (from-to)425-431
Number of pages7
JournalSkeletal Radiology
Issue number6
StatePublished - Aug 1 1993


  • Bone mineral density
  • Indention test
  • Osteoporosis
  • Proximal femur
  • Singh index
  • Structural change

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging


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