Amygdala activation in the processing of neutral faces in social anxiety disorder: Is neutral really neutral?

Rebecca E. Cooney; Lauren Y. Atlas; Jutta Joormann; Fanny Eugène; Ian H. Gotlib

doi:10.1016/j.pscychresns.2006.05.003

Amygdala activation in the processing of neutral faces in social anxiety disorder: Is neutral really neutral?

Rebecca E. Cooney, Lauren Y. Atlas, Jutta Joormann, Fanny Eugène, Ian H. Gotlib

Psychology

Research output: Contribution to journal › Article › peer-review

171 Scopus citations

Abstract

Previous research has suggested that Social Anxiety Disorder (SAD) is associated with a tendency to interpret ambiguous social stimuli in a threatening manner. The present study used event-related functional magnetic resonance imaging to examine patterns of neural activation in response to the processing of neutral facial expressions in individuals diagnosed with SAD and healthy controls (CTLs). The SAD participants exhibited a different pattern of amygdala activation in response to neutral faces than did the CTL participants, suggesting a neural basis for the biased processing of ambiguous social information in SAD individuals.

Original language	English (US)
Pages (from-to)	55-59
Number of pages	5
Journal	Psychiatry Research - Neuroimaging
Volume	148
Issue number	1
DOIs	https://doi.org/10.1016/j.pscychresns.2006.05.003
State	Published - Nov 22 2006

Keywords

Amygdala
Functional magnetic resonance imaging (fMRI)
Social anxiety disorder
Social phobia

ASJC Scopus subject areas

Psychiatry and Mental health
Radiology Nuclear Medicine and imaging
Biological Psychiatry
Psychology(all)

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title = "Amygdala activation in the processing of neutral faces in social anxiety disorder: Is neutral really neutral?",

abstract = "Previous research has suggested that Social Anxiety Disorder (SAD) is associated with a tendency to interpret ambiguous social stimuli in a threatening manner. The present study used event-related functional magnetic resonance imaging to examine patterns of neural activation in response to the processing of neutral facial expressions in individuals diagnosed with SAD and healthy controls (CTLs). The SAD participants exhibited a different pattern of amygdala activation in response to neutral faces than did the CTL participants, suggesting a neural basis for the biased processing of ambiguous social information in SAD individuals.",

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note = "Funding Information: We thank Anne Sawyer-Glover, Jenni Champion, Kathryn Dingman, and Faith Brozovich for their assistance. This research was supported by NIMH Grant MH59259 to Ian H. Gotlib. Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",

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AU - Gotlib, Ian H.

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N2 - Previous research has suggested that Social Anxiety Disorder (SAD) is associated with a tendency to interpret ambiguous social stimuli in a threatening manner. The present study used event-related functional magnetic resonance imaging to examine patterns of neural activation in response to the processing of neutral facial expressions in individuals diagnosed with SAD and healthy controls (CTLs). The SAD participants exhibited a different pattern of amygdala activation in response to neutral faces than did the CTL participants, suggesting a neural basis for the biased processing of ambiguous social information in SAD individuals.

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Amygdala activation in the processing of neutral faces in social anxiety disorder: Is neutral really neutral?

Abstract

Keywords

ASJC Scopus subject areas

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