Alzheimer's-disease-related protein in geriatric schizophrenic patients with cognitive impairment

Peter Powchik, Michael Davidson, Charles Nemeroff, Vahram Haroutunian, Dushyant Purohit, Miklos Losonczy, Garth Bissette, Daniel Perl, Hossein Ghanbari, Barney Miller, Kenneth L. Davis

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32 Scopus citations

Abstract

The authors compared Alz-50 immunoreactivity in the brain tissue of nine cognitively impaired elderly schizophrenic patients and 13 elderly comparison subjects, both without neuritic plaques or neurofibrillary tangles, and 13 patients with Alzheimer's disease. Alz-50 reactivity was absent in the schizophrenic patients, indicating that geriatric, cognitively impaired patients are unlikely to display the pathology of Alzheimer's disease.

Original languageEnglish
Pages (from-to)1726-1727
Number of pages2
JournalAmerican Journal of Psychiatry
Volume150
Issue number11
StatePublished - Dec 1 1993
Externally publishedYes

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ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Powchik, P., Davidson, M., Nemeroff, C., Haroutunian, V., Purohit, D., Losonczy, M., Bissette, G., Perl, D., Ghanbari, H., Miller, B., & Davis, K. L. (1993). Alzheimer's-disease-related protein in geriatric schizophrenic patients with cognitive impairment. American Journal of Psychiatry, 150(11), 1726-1727.