Alzheimer's-disease-related protein in geriatric schizophrenic patients with cognitive impairment

Peter Powchik, Michael Davidson, Charles B. Nemeroff, Vahram Haroutunian, Dushyant Purohit, Miklos Losonczy, Garth Bissette, Daniel Perl, Hossein Ghanbari, Barney Miller, Kenneth L. Davis

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

The authors compared Alz-50 immunoreactivity in the brain tissue of nine cognitively impaired elderly schizophrenic patients and 13 elderly comparison subjects, both without neuritic plaques or neurofibrillary tangles, and 13 patients with Alzheimer's disease. Alz-50 reactivity was absent in the schizophrenic patients, indicating that geriatric, cognitively impaired patients are unlikely to display the pathology of Alzheimer's disease.

Original languageEnglish (US)
Pages (from-to)1726-1727
Number of pages2
JournalAmerican Journal of Psychiatry
Volume150
Issue number11
DOIs
StatePublished - 1993

ASJC Scopus subject areas

  • Psychiatry and Mental health

Fingerprint Dive into the research topics of 'Alzheimer's-disease-related protein in geriatric schizophrenic patients with cognitive impairment'. Together they form a unique fingerprint.

  • Cite this

    Powchik, P., Davidson, M., Nemeroff, C. B., Haroutunian, V., Purohit, D., Losonczy, M., Bissette, G., Perl, D., Ghanbari, H., Miller, B., & Davis, K. L. (1993). Alzheimer's-disease-related protein in geriatric schizophrenic patients with cognitive impairment. American Journal of Psychiatry, 150(11), 1726-1727. https://doi.org/10.1176/ajp.150.11.1726