Alternatives to immunosuppressive drugs in human islet transplantation.

Alison Anne Cotterell, Norma S Kenyon

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Although intensive insulin therapy has resulted in improved metabolic control and decreases in the incidence of complications, the occurrence of severe hypoglycemia remains an issue, as does the continued potential for complications. Islet transplantation, a promising treatment for type I diabetes, has been shown to improve blood sugar levels and decrease or even abrogate the incidence of hypoglycemia. The lack of tissue availability and the toxic effects of immunosuppressants, however, limit the application of islet transplantation as a cure for diabetes. This article discusses possible alternatives to immunosuppressive drugs in human islet transplantations.

Original languageEnglish
Pages (from-to)377-382
Number of pages6
JournalCurr Diab Rep
Volume2
Issue number4
StatePublished - Aug 1 2002

Fingerprint

Islets of Langerhans Transplantation
Immunosuppressive Agents
Hypoglycemia
Pharmaceutical Preparations
Poisons
Incidence
Type 1 Diabetes Mellitus
Blood Glucose
Insulin
Therapeutics

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Cardiology and Cardiovascular Medicine

Cite this

Alternatives to immunosuppressive drugs in human islet transplantation. / Cotterell, Alison Anne; Kenyon, Norma S.

In: Curr Diab Rep, Vol. 2, No. 4, 01.08.2002, p. 377-382.

Research output: Contribution to journalArticle

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