Abstract
Although intensive insulin therapy has resulted in improved metabolic control and decreases in the incidence of complications, the occurrence of severe hypoglycemia remains an issue, as does the continued potential for complications. Islet transplantation, a promising treatment for type I diabetes, has been shown to improve blood sugar levels and decrease or even abrogate the incidence of hypoglycemia. The lack of tissue availability and the toxic effects of immunosuppressants, however, limit the application of islet transplantation as a cure for diabetes. This article discusses possible alternatives to immunosuppressive drugs in human islet transplantations.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 377-382 |
| Number of pages | 6 |
| Journal | Current diabetes reports |
| Volume | 2 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 2002 |
ASJC Scopus subject areas
- Internal Medicine
- Endocrinology, Diabetes and Metabolism
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Cotterell, A. A., & Kenyon, N. S. (2002). Alternatives to immunosuppressive drugs in human islet transplantation. Current diabetes reports, 2(4), 377-382. https://doi.org/10.1007/s11892-002-0030-5