Altered responsiveness during hyperventilation-induced EEG slowing: A non- epileptic phenomenon in normal children

M. A. Epstein, M. Duchowny, P. Jayakar, T. J. Resnick, L. A. Alvarez

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

The relation between hyperventilation (HV)-induced high-amplitude rhythmical slowing (HIHARS) and altered responsiveness without generalized spike and wave activity has not been clearly defined. To test whether altered responsiveness is a nonspecific physiologic response rather than a symptom of generalized epilepsy, we assessed verbal recall ability and motor response testing in 12 healthy nonepileptic children (mean age 9.6 years). Both tasks were administered as a baseline before HV, during HV but before onset of EEG slowing, and during HIHARS. Verbal recall and motor responsiveness remained unchanged during baseline and HV before onset of slowing. During HIHARS, all children exhibited impaired verbal recall (p < 0.005) and 8 of 12 failed to respond to repeated auditory clicks (p < 0.005). Our findings indicate that in a normal setting, responsiveness may be impaired during HV in healthy nonepileptic children.

Original languageEnglish
Pages (from-to)1204-1207
Number of pages4
JournalEpilepsia
Volume35
Issue number6
DOIs
StatePublished - Dec 20 1994

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Hyperventilation
Electroencephalography
Generalized Epilepsy

Keywords

  • Absence seizure
  • Altered consciousness
  • High-amplitude rhythmic slowing
  • Hyperventilation
  • Nonepileptic children

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Altered responsiveness during hyperventilation-induced EEG slowing : A non- epileptic phenomenon in normal children. / Epstein, M. A.; Duchowny, M.; Jayakar, P.; Resnick, T. J.; Alvarez, L. A.

In: Epilepsia, Vol. 35, No. 6, 20.12.1994, p. 1204-1207.

Research output: Contribution to journalArticle

Epstein, M. A. ; Duchowny, M. ; Jayakar, P. ; Resnick, T. J. ; Alvarez, L. A. / Altered responsiveness during hyperventilation-induced EEG slowing : A non- epileptic phenomenon in normal children. In: Epilepsia. 1994 ; Vol. 35, No. 6. pp. 1204-1207.
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