Altered mechanics of tibial cartilage following joint immobilization in a canine model

Lori A. Setton, Charles H. Perry, Michelle A. LeRoux, Jean Y. Wang, David S. Howell, Herman S Cheung

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

To study the effect of immobilization, the compressive and shear properties of articular cartilage were quantified at sites corresponding to those of elevated MMP staining on the tibial plateau of mongrel dogs. Cartilage samples were tested in compression and torsion on a displacement-controlled rheometer. The samples were weighed after testing and again after lyophilization to determine water content as the percentage of tissue wet weight. The results support the hypothesis that knee joint immobilization will produce deleterious changes in cartilage function at the tibial plateau.

Original languageEnglish
Title of host publicationAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Place of PublicationFairfield, NJ, United States
PublisherASME
Pages71-72
Number of pages2
Volume42
ISBN (Print)0791816117
StatePublished - Dec 1 1999
Event1999 Bioengineering Conference - Big Sky, MT, USA
Duration: Jun 16 1999Jun 20 1999

Other

Other1999 Bioengineering Conference
CityBig Sky, MT, USA
Period6/16/996/20/99

Fingerprint

Cartilage
Mechanics
Rheometers
Torsional stress
Water content
Tissue
Testing

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Setton, L. A., Perry, C. H., LeRoux, M. A., Wang, J. Y., Howell, D. S., & Cheung, H. S. (1999). Altered mechanics of tibial cartilage following joint immobilization in a canine model. In American Society of Mechanical Engineers, Bioengineering Division (Publication) BED (Vol. 42, pp. 71-72). Fairfield, NJ, United States: ASME.

Altered mechanics of tibial cartilage following joint immobilization in a canine model. / Setton, Lori A.; Perry, Charles H.; LeRoux, Michelle A.; Wang, Jean Y.; Howell, David S.; Cheung, Herman S.

American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Vol. 42 Fairfield, NJ, United States : ASME, 1999. p. 71-72.

Research output: Chapter in Book/Report/Conference proceedingChapter

Setton, LA, Perry, CH, LeRoux, MA, Wang, JY, Howell, DS & Cheung, HS 1999, Altered mechanics of tibial cartilage following joint immobilization in a canine model. in American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. vol. 42, ASME, Fairfield, NJ, United States, pp. 71-72, 1999 Bioengineering Conference, Big Sky, MT, USA, 6/16/99.
Setton LA, Perry CH, LeRoux MA, Wang JY, Howell DS, Cheung HS. Altered mechanics of tibial cartilage following joint immobilization in a canine model. In American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Vol. 42. Fairfield, NJ, United States: ASME. 1999. p. 71-72
Setton, Lori A. ; Perry, Charles H. ; LeRoux, Michelle A. ; Wang, Jean Y. ; Howell, David S. ; Cheung, Herman S. / Altered mechanics of tibial cartilage following joint immobilization in a canine model. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. Vol. 42 Fairfield, NJ, United States : ASME, 1999. pp. 71-72
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