This is the first reported case of a single gastrointestinal malignancy in an adult in which both alpha-fetoprotein and carcinoembryonic antigen were detected in similar tumor tissue. Hepatic metastases from gastric adenocarcinoma were found to contain both AFP and CEA. The primary tumor contained only carcinoembryonic antigen. Alpha-fetoprotein may represent antigen produced locally by hepatic tissue in response to the presence of tumor; its function is speculative.
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