Alpha-fetorprotein and carcinoembryonic antigen in a case of gastric carcinoma metastatic to the liver

James L. Bierfeld, Monroe I. Scheiner, Duane R. Schultz, Maria D. Moral, Arvey I. Rogers

Research output: Contribution to journalArticle

24 Scopus citations


This is the first reported case of a single gastrointestinal malignancy in an adult in which both alpha-fetoprotein and carcinoembryonic antigen were detected in similar tumor tissue. Hepatic metastases from gastric adenocarcinoma were found to contain both AFP and CEA. The primary tumor contained only carcinoembryonic antigen. Alpha-fetoprotein may represent antigen produced locally by hepatic tissue in response to the presence of tumor; its function is speculative.

Original languageEnglish
Pages (from-to)517-520
Number of pages4
JournalThe American Journal of Digestive Diseases
Issue number6
StatePublished - Jun 1 1973
Externally publishedYes


ASJC Scopus subject areas

  • Gastroenterology
  • Medicine(all)

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