Alopecia areata: A pathological study of nonresponder patients

P. A. Fanti, Antonella Tosti, F. Bardazzi, L. Guerra, R. Morelli, N. Cameli

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13 Scopus citations

Abstract

Fourteen patients, four male and 10 female and ranging in age from 11 to 57 years, affected by longstanding alopecia areata that had not responded to sensitizing treatments, were submitted to scalp biopsy. Five patients had alopecia totalis and nine had alopecia universalis. The biopsy was performed on a scalp area that had been bald for ≥1 year. We distinguished four distinct pathological patterns, which we termed 'established bald patch,' 'early regrowth,' 'telogen,' and 'scarring,' 'in four, seven, one, and two patients, respectively. Our study shows that, from a pathological point of view, nonresponder patients constitute a heterogeneous population. The pathological study of the scalp helps predict therapeutic failure only in the small proportion of nonresponder patients that shows a scarring pathological pattern.

Original languageEnglish
Pages (from-to)167-170
Number of pages4
JournalAmerican Journal of Dermatopathology
Volume16
Issue number2
StatePublished - Jan 1 1994
Externally publishedYes

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Keywords

  • Alopecia areata
  • Histopathology
  • Nonresponder patients
  • Scarring alopecia

ASJC Scopus subject areas

  • Dermatology
  • Pathology and Forensic Medicine

Cite this

Fanti, P. A., Tosti, A., Bardazzi, F., Guerra, L., Morelli, R., & Cameli, N. (1994). Alopecia areata: A pathological study of nonresponder patients. American Journal of Dermatopathology, 16(2), 167-170.