Abstract
A 13-year-old HIV-infected girl presented with a rapidly progressive akinetic-rigid syndrome. Cranial magnetic resonance imaging revealed bilateral centrum semiovale lesions extending into the basal ganglia. Detailed histopathological study of a biopsy specimen from the involved regions resulted in a diagnosis of progressive multifocal leukoencephalopathy (PML). This case illustrates that an akinetic-rigid syndrome may be a rare presentation of PML. HIV-related PML may have unusual radiological features. Brain biopsy may be necessary to confirm PML in cases associated with atypical clinical and radiological presentations.
Original language | English (US) |
---|---|
Pages (from-to) | 113-116 |
Number of pages | 4 |
Journal | Movement Disorders |
Volume | 8 |
Issue number | 1 |
DOIs | |
State | Published - 1993 |
Keywords
- Acquired immunodeficiency syndrome
- Akinetic‐rigid syndrome
- Basal ganglia diseases
- Bradykinesia
- Magnetic resonance imaging
- Parkinsonism
- Progressive multifocal leukoencephalopathy
ASJC Scopus subject areas
- Neurology
- Clinical Neurology