Aging effects on motor units in the human thyroarytenoid muscle

Naoya Takeda, Giovana Thomas, Christy L. Ludlow

Research output: Contribution to journalArticle

49 Citations (Scopus)

Abstract

Objectives: To determine whether age differences are present in the human laryngeal thyroarytenoid muscle that would indicate that different normative values would be needed for identifying motor unit abnormalities. Study Design: Twenty-six consecutively recruited healthy subjects between the ages of 21 and 72 years participated in a laryngeal electromyography study. Methods: Bipolar needle electrodes were used to record motor unit action potentials from several locations in the right and left thyroarytenoid muscles of each subject. The duration of a motor unit was measured when at least 10 firings of the same motor unit could be identified. On the average, four units were measured per muscle. Results: In the subjects less than 60 years of age, motor unit duration did not increase significantly with age. However, motor units from subjects greater than 60 years of age had longer durations than those from subjects less than 60 years of age (P < .00005), and 25% of the units measured in subjects greater than 60 years of age had longer durations than any of the units measured in subjects less than 60 years of age. Further, the older subjects differed from each other in their mean unit durations (P < .0001). In subjects less than 60 years of age, significantly longer durations were found for units innervated by the longer, left-side recurrent laryngeal nerve in comparison with the right-side nerve (P = .005). Conclusions: Different mean and SD values should be used for patients less than and greater than 60 years of age and for the right and left sides, when evaluating motor units in the thyroarytenoid muscles.

Original languageEnglish
Pages (from-to)1018-1025
Number of pages8
JournalLaryngoscope
Volume110
Issue number6
StatePublished - Jun 1 2000
Externally publishedYes

Fingerprint

Laryngeal Muscles
Recurrent Laryngeal Nerve
Electromyography
Action Potentials
Needles
Healthy Volunteers
Electrodes
Muscles

Keywords

  • Aging
  • Electromyography
  • Motor unit
  • Neuropathy
  • Recurrent laryngeal nerve
  • Thyroarytenoid muscle

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Takeda, N., Thomas, G., & Ludlow, C. L. (2000). Aging effects on motor units in the human thyroarytenoid muscle. Laryngoscope, 110(6), 1018-1025.

Aging effects on motor units in the human thyroarytenoid muscle. / Takeda, Naoya; Thomas, Giovana; Ludlow, Christy L.

In: Laryngoscope, Vol. 110, No. 6, 01.06.2000, p. 1018-1025.

Research output: Contribution to journalArticle

Takeda, N, Thomas, G & Ludlow, CL 2000, 'Aging effects on motor units in the human thyroarytenoid muscle', Laryngoscope, vol. 110, no. 6, pp. 1018-1025.
Takeda, Naoya ; Thomas, Giovana ; Ludlow, Christy L. / Aging effects on motor units in the human thyroarytenoid muscle. In: Laryngoscope. 2000 ; Vol. 110, No. 6. pp. 1018-1025.
@article{dffc0bfcaa2c4aa7ae615dddaac43325,
title = "Aging effects on motor units in the human thyroarytenoid muscle",
abstract = "Objectives: To determine whether age differences are present in the human laryngeal thyroarytenoid muscle that would indicate that different normative values would be needed for identifying motor unit abnormalities. Study Design: Twenty-six consecutively recruited healthy subjects between the ages of 21 and 72 years participated in a laryngeal electromyography study. Methods: Bipolar needle electrodes were used to record motor unit action potentials from several locations in the right and left thyroarytenoid muscles of each subject. The duration of a motor unit was measured when at least 10 firings of the same motor unit could be identified. On the average, four units were measured per muscle. Results: In the subjects less than 60 years of age, motor unit duration did not increase significantly with age. However, motor units from subjects greater than 60 years of age had longer durations than those from subjects less than 60 years of age (P < .00005), and 25{\%} of the units measured in subjects greater than 60 years of age had longer durations than any of the units measured in subjects less than 60 years of age. Further, the older subjects differed from each other in their mean unit durations (P < .0001). In subjects less than 60 years of age, significantly longer durations were found for units innervated by the longer, left-side recurrent laryngeal nerve in comparison with the right-side nerve (P = .005). Conclusions: Different mean and SD values should be used for patients less than and greater than 60 years of age and for the right and left sides, when evaluating motor units in the thyroarytenoid muscles.",
keywords = "Aging, Electromyography, Motor unit, Neuropathy, Recurrent laryngeal nerve, Thyroarytenoid muscle",
author = "Naoya Takeda and Giovana Thomas and Ludlow, {Christy L.}",
year = "2000",
month = "6",
day = "1",
language = "English",
volume = "110",
pages = "1018--1025",
journal = "Laryngoscope",
issn = "0023-852X",
publisher = "Wiley-Blackwell",
number = "6",

}

TY - JOUR

T1 - Aging effects on motor units in the human thyroarytenoid muscle

AU - Takeda, Naoya

AU - Thomas, Giovana

AU - Ludlow, Christy L.

PY - 2000/6/1

Y1 - 2000/6/1

N2 - Objectives: To determine whether age differences are present in the human laryngeal thyroarytenoid muscle that would indicate that different normative values would be needed for identifying motor unit abnormalities. Study Design: Twenty-six consecutively recruited healthy subjects between the ages of 21 and 72 years participated in a laryngeal electromyography study. Methods: Bipolar needle electrodes were used to record motor unit action potentials from several locations in the right and left thyroarytenoid muscles of each subject. The duration of a motor unit was measured when at least 10 firings of the same motor unit could be identified. On the average, four units were measured per muscle. Results: In the subjects less than 60 years of age, motor unit duration did not increase significantly with age. However, motor units from subjects greater than 60 years of age had longer durations than those from subjects less than 60 years of age (P < .00005), and 25% of the units measured in subjects greater than 60 years of age had longer durations than any of the units measured in subjects less than 60 years of age. Further, the older subjects differed from each other in their mean unit durations (P < .0001). In subjects less than 60 years of age, significantly longer durations were found for units innervated by the longer, left-side recurrent laryngeal nerve in comparison with the right-side nerve (P = .005). Conclusions: Different mean and SD values should be used for patients less than and greater than 60 years of age and for the right and left sides, when evaluating motor units in the thyroarytenoid muscles.

AB - Objectives: To determine whether age differences are present in the human laryngeal thyroarytenoid muscle that would indicate that different normative values would be needed for identifying motor unit abnormalities. Study Design: Twenty-six consecutively recruited healthy subjects between the ages of 21 and 72 years participated in a laryngeal electromyography study. Methods: Bipolar needle electrodes were used to record motor unit action potentials from several locations in the right and left thyroarytenoid muscles of each subject. The duration of a motor unit was measured when at least 10 firings of the same motor unit could be identified. On the average, four units were measured per muscle. Results: In the subjects less than 60 years of age, motor unit duration did not increase significantly with age. However, motor units from subjects greater than 60 years of age had longer durations than those from subjects less than 60 years of age (P < .00005), and 25% of the units measured in subjects greater than 60 years of age had longer durations than any of the units measured in subjects less than 60 years of age. Further, the older subjects differed from each other in their mean unit durations (P < .0001). In subjects less than 60 years of age, significantly longer durations were found for units innervated by the longer, left-side recurrent laryngeal nerve in comparison with the right-side nerve (P = .005). Conclusions: Different mean and SD values should be used for patients less than and greater than 60 years of age and for the right and left sides, when evaluating motor units in the thyroarytenoid muscles.

KW - Aging

KW - Electromyography

KW - Motor unit

KW - Neuropathy

KW - Recurrent laryngeal nerve

KW - Thyroarytenoid muscle

UR - http://www.scopus.com/inward/record.url?scp=0034044467&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034044467&partnerID=8YFLogxK

M3 - Article

VL - 110

SP - 1018

EP - 1025

JO - Laryngoscope

JF - Laryngoscope

SN - 0023-852X

IS - 6

ER -