Aging, cytomegalovirus (CMV) and influenza vaccine responses

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

Influenza vaccination is less effective in elderly as compared to young individuals. Several studies have identified immune biomarkers able to predict a protective humoral immune response to the vaccine. In this review, we summarize current knowledge on the effects of aging on influenza vaccine responses and on biomarkers so far identified, and we discuss the relevance of latent cytomegalovirus (CMV) infection on these vaccine responses.

Original languageEnglish (US)
Pages (from-to)682-690
Number of pages9
JournalHuman Vaccines and Immunotherapeutics
Volume12
Issue number3
DOIs
StatePublished - Mar 3 2016

Keywords

  • Aging
  • B cells
  • CMV
  • influenza vaccine

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Pharmacology

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