Aging and cancer.

Debashish Misra, Pearl H. Seo, Harvey Jay Cohen

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


A substantial increase in the number of elderly people in the populations of developed nations in the coming years has been projected. Persons 65 years and older are at significantly higher risk of developing cancer when compared to younger individuals. There is a resulting increase in cancer incidence as well as mortality in this advanced age group. It is important to know how changes in physiological reserve and functional status in elderly patients, polypharmacy issues, comorbidities, and other age-related problems can affect cancer prognosis and management. Elderly patients are not adequately represented in clinical trials, thus creating a relative lack of information related to specific issues about elderly cancer patients and their care. Nevertheless, there is a substantial amount of guidance available, and in this review we will address selected issues of importance when considering the approach to the older cancer patient.

Original languageEnglish (US)
Pages (from-to)457-465
Number of pages9
JournalClinical advances in hematology & oncology : H&O
Issue number7
StatePublished - Jul 2004
Externally publishedYes

ASJC Scopus subject areas

  • Hematology
  • Oncology


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