Abstract
Ageing is associated with a progressive decline of immune responsiveness to exogenous antigens and increasing incidence of autoimmune phenomena [1,2]. Many studies have been focussed on the mechanisms of the immunologic features of ageing. Alterations in cellular components of the immune system rather than in the extracellular milieu seem to account for most of the variations of immune competence in ageing [3].
| Original language | English |
|---|---|
| Pages (from-to) | 231-233 |
| Number of pages | 3 |
| Journal | Immunology Letters |
| Volume | 40 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jun 1 1994 |
| Externally published | Yes |
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Keywords
- Autoimmunity
- Cell differentiation
- Cell proliferation
- Exogenous antigen
- Interleukin-2
- Thymus
ASJC Scopus subject areas
- Immunology
- Immunology and Allergy
Cite this
Ageing and genetic control of immune responsiveness. / Doria, Gino; Frasca, Daniela.
In: Immunology Letters, Vol. 40, No. 3, 01.06.1994, p. 231-233.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ageing and genetic control of immune responsiveness
AU - Doria, Gino
AU - Frasca, Daniela
PY - 1994/6/1
Y1 - 1994/6/1
N2 - Ageing is associated with a progressive decline of immune responsiveness to exogenous antigens and increasing incidence of autoimmune phenomena [1,2]. Many studies have been focussed on the mechanisms of the immunologic features of ageing. Alterations in cellular components of the immune system rather than in the extracellular milieu seem to account for most of the variations of immune competence in ageing [3].
AB - Ageing is associated with a progressive decline of immune responsiveness to exogenous antigens and increasing incidence of autoimmune phenomena [1,2]. Many studies have been focussed on the mechanisms of the immunologic features of ageing. Alterations in cellular components of the immune system rather than in the extracellular milieu seem to account for most of the variations of immune competence in ageing [3].
KW - Autoimmunity
KW - Cell differentiation
KW - Cell proliferation
KW - Exogenous antigen
KW - Interleukin-2
KW - Thymus
UR - http://www.scopus.com/inward/record.url?scp=0027936390&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027936390&partnerID=8YFLogxK
U2 - 10.1016/0165-2478(94)00061-1
DO - 10.1016/0165-2478(94)00061-1
M3 - Article
C2 - 7959892
AN - SCOPUS:0027936390
VL - 40
SP - 231
EP - 233
JO - Immunology Letters
JF - Immunology Letters
SN - 0165-2478
IS - 3
ER -