Abstract
Ageing is associated with a progressive decline of immune responsiveness to exogenous antigens and increasing incidence of autoimmune phenomena [1,2]. Many studies have been focussed on the mechanisms of the immunologic features of ageing. Alterations in cellular components of the immune system rather than in the extracellular milieu seem to account for most of the variations of immune competence in ageing [3].
| Original language | English (US) |
|---|---|
| Pages (from-to) | 231-233 |
| Number of pages | 3 |
| Journal | Immunology Letters |
| Volume | 40 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jun 1 1994 |
| Externally published | Yes |
Keywords
- Autoimmunity
- Cell differentiation
- Cell proliferation
- Exogenous antigen
- Interleukin-2
- Thymus
ASJC Scopus subject areas
- Immunology
- Immunology and Allergy
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Cite this
Doria, G., & Frasca, D. (1994). Ageing and genetic control of immune responsiveness. Immunology Letters, 40(3), 231-233. https://doi.org/10.1016/0165-2478(94)00061-1