Ageing and genetic control of immune responsiveness

Gino Doria, Daniela Frasca

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Ageing is associated with a progressive decline of immune responsiveness to exogenous antigens and increasing incidence of autoimmune phenomena [1,2]. Many studies have been focussed on the mechanisms of the immunologic features of ageing. Alterations in cellular components of the immune system rather than in the extracellular milieu seem to account for most of the variations of immune competence in ageing [3].

Original languageEnglish (US)
Pages (from-to)231-233
Number of pages3
JournalImmunology Letters
Volume40
Issue number3
DOIs
StatePublished - Jun 1 1994
Externally publishedYes

Keywords

  • Autoimmunity
  • Cell differentiation
  • Cell proliferation
  • Exogenous antigen
  • Interleukin-2
  • Thymus

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

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