Age of disease onset influences cognition in Parkinson's disease

Heather L. Katzen, Bonnie Levin, Maria Llabre

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

It is controversial whether age of disease onset is related to cognitive decline in Parkinson's disease (PD). We administered 7 cognitive measures assessing visuospatial skills, memory, and executive functions to 222 patients with idiopathic PD and 108 normal control participants. Regression analyses demonstrated that older age of disease onset consistently predicted cognitive decline above and beyond normative aging and duration of illness. These findings suggest that older age of disease onset is a critical determinant of cognitive deterioration in PD.

Original languageEnglish
Pages (from-to)285-290
Number of pages6
JournalJournal of the International Neuropsychological Society
Volume4
Issue number3
StatePublished - May 1 1998

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Age of Onset
Cognition
Parkinson Disease
Executive Function
Regression Analysis
Cognitive Dysfunction

Keywords

  • Age of onset
  • Cognition
  • Cognitive decline
  • Parkinson's disease

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Psychiatry and Mental health
  • Neuroscience(all)
  • Psychology(all)

Cite this

Age of disease onset influences cognition in Parkinson's disease. / Katzen, Heather L.; Levin, Bonnie; Llabre, Maria.

In: Journal of the International Neuropsychological Society, Vol. 4, No. 3, 01.05.1998, p. 285-290.

Research output: Contribution to journalArticle

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