Advances in the diagnosis and treatment of infectious endophthalmitis

R. D. Brod, H. W. Flynn

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


Although advances in the diagnosis and management of infectious endophthalmitis have improved the overall prognosis, it still remains a challenge to the clinician. Diagnostic and therapeutic approaches continue to evolve. Enzymatic, immunologic, and molecular genetic technology now enable rapid and specific diagnosis of intraocular infection. Prompt pars plana vitrectomy, although still controversial in the management of endophthalmitis, appears to be an important adjunct in the treatment of moderate to severe cases. Increased awareness of the organisms responsible for delayed-onset postoperative endophthalmitis has led to earlier diagnosis and effective treatment. The recognition of Bacillus species as a common cause of posttraumatic endophthalmitis as well as better characterization of its antibiotic susceptibility may help improve the prognosis of this severe intraocular infection. Newer, less-toxic systemic antifungal medications are available that can be used alone or in conjunction with local ocular therapy for endogenous fungal endophthalmitis.

Original languageEnglish (US)
Pages (from-to)306-314
Number of pages9
JournalCurrent opinion in ophthalmology
Issue number3
StatePublished - Jan 1 1991
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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