Abstract
The authors describe a 58-year-old woman who experienced an erythema multiforme-like reaction following therapy with cefamandole naftate. Histologically, findings were consistent with erythema multiforme, but diffuse linear position of IgA was demonstrated at the dermo-epidermal junction by direct immunofluorescence. Ultrastructurally, deposits were located beneath the basal lamina, around the anchoring fibrils. These observations illustrate that adult linear IgA bullous dermatosis can mimic the clinical and histological features of erythema multiforme and suggest the possibility of drug-induced pathogenesis.
| Original language | English |
|---|---|
| Pages (from-to) | 445-450 |
| Number of pages | 6 |
| Journal | Cleveland Clinic Journal of Medicine |
| Volume | 54 |
| Issue number | 5 |
| State | Published - Dec 1 1987 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Adult linear IgA disease associated with an erythema multiforme-like drug reaction. / Argenyi, Z. B.; Bergfeld, W. F.; Valenzuela, R.; McMahon, J. T.; Taylor, J. S.
In: Cleveland Clinic Journal of Medicine, Vol. 54, No. 5, 01.12.1987, p. 445-450.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Adult linear IgA disease associated with an erythema multiforme-like drug reaction
AU - Argenyi, Z. B.
AU - Bergfeld, W. F.
AU - Valenzuela, R.
AU - McMahon, J. T.
AU - Taylor, J. S.
PY - 1987/12/1
Y1 - 1987/12/1
N2 - The authors describe a 58-year-old woman who experienced an erythema multiforme-like reaction following therapy with cefamandole naftate. Histologically, findings were consistent with erythema multiforme, but diffuse linear position of IgA was demonstrated at the dermo-epidermal junction by direct immunofluorescence. Ultrastructurally, deposits were located beneath the basal lamina, around the anchoring fibrils. These observations illustrate that adult linear IgA bullous dermatosis can mimic the clinical and histological features of erythema multiforme and suggest the possibility of drug-induced pathogenesis.
AB - The authors describe a 58-year-old woman who experienced an erythema multiforme-like reaction following therapy with cefamandole naftate. Histologically, findings were consistent with erythema multiforme, but diffuse linear position of IgA was demonstrated at the dermo-epidermal junction by direct immunofluorescence. Ultrastructurally, deposits were located beneath the basal lamina, around the anchoring fibrils. These observations illustrate that adult linear IgA bullous dermatosis can mimic the clinical and histological features of erythema multiforme and suggest the possibility of drug-induced pathogenesis.
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UR - http://www.scopus.com/inward/citedby.url?scp=0023595122&partnerID=8YFLogxK
M3 - Article
C2 - 2959399
AN - SCOPUS:0023595122
VL - 54
SP - 445
EP - 450
JO - Cleveland Clinic Journal of Medicine
JF - Cleveland Clinic Journal of Medicine
SN - 0891-1150
IS - 5
ER -