Adrenocortical carcinoma with cerebral metastasis in a child: Case report and review of the literature

Rita L. Romaguera, Alireza Minagar, Jocelyn H. Bruce, Jonathan R. Jagid, Steven Falcone, Richard G. Curless, John Ragheb, Glenn Morrison

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Objective and importance: Adrenocortical carcinoma (ACC) is rare in the pediatric population, and brain metastasis seldom occurs. Clinical presentation: The authors report a case of metastatic ACC to the brain in a 9-year-old patient who had an adrenal cortex neoplasm removed at 4 years of age, and was free of symptoms for 5 years. Two weeks before admission she complained of blurred vision in both eyes. Intervention: Examination revealed bilateral papilledema, and a Magnetic Resonance Imaging (MRI) of the brain revealed a mass in the left lateral ventricle with extensive vasogenic edema and hydrocephalus. The tumor was removed, and histopathologic examination demonstrated metastatic ACC. Conclusion: Although ACC is a rare neoplasm it must be considered in the differential diagnosis of cerebral lesions in patients with a history of this tumor. Periodic long-term brain imaging is suggested as part of the follow up in patients with adrenocortical neoplasms.

Original languageEnglish (US)
Pages (from-to)46-50
Number of pages5
JournalClinical Neurology and Neurosurgery
Issue number1
StatePublished - May 2 2001


  • Adrenocortical carcinoma
  • Adrenocortical neoplasm
  • Brain metastasis
  • Brain tumor

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Neurology


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