Adrenocortical carcinoma with cerebral metastasis in a child: Case report and review of the literature

Rita L. Romaguera, Alireza Minagar, Jocelyn H. Bruce, Jonathan Jagid, Steven Falcone, Richard G. Curless, John Ragheb, Glenn Morrison

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Objective and importance: Adrenocortical carcinoma (ACC) is rare in the pediatric population, and brain metastasis seldom occurs. Clinical presentation: The authors report a case of metastatic ACC to the brain in a 9-year-old patient who had an adrenal cortex neoplasm removed at 4 years of age, and was free of symptoms for 5 years. Two weeks before admission she complained of blurred vision in both eyes. Intervention: Examination revealed bilateral papilledema, and a Magnetic Resonance Imaging (MRI) of the brain revealed a mass in the left lateral ventricle with extensive vasogenic edema and hydrocephalus. The tumor was removed, and histopathologic examination demonstrated metastatic ACC. Conclusion: Although ACC is a rare neoplasm it must be considered in the differential diagnosis of cerebral lesions in patients with a history of this tumor. Periodic long-term brain imaging is suggested as part of the follow up in patients with adrenocortical neoplasms.

Original languageEnglish
Pages (from-to)46-50
Number of pages5
JournalClinical Neurology and Neurosurgery
Volume103
Issue number1
DOIs
StatePublished - May 2 2001

Fingerprint

Adrenocortical Carcinoma
Neoplasm Metastasis
Neoplasms
Brain
Adrenal Cortex Neoplasms
Papilledema
Lateral Ventricles
Hydrocephalus
Neuroimaging
Heart Ventricles
Edema
Differential Diagnosis
Magnetic Resonance Imaging
Pediatrics
Population

Keywords

  • Adrenocortical carcinoma
  • Adrenocortical neoplasm
  • Brain metastasis
  • Brain tumor

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Neurology

Cite this

Adrenocortical carcinoma with cerebral metastasis in a child : Case report and review of the literature. / Romaguera, Rita L.; Minagar, Alireza; Bruce, Jocelyn H.; Jagid, Jonathan; Falcone, Steven; Curless, Richard G.; Ragheb, John; Morrison, Glenn.

In: Clinical Neurology and Neurosurgery, Vol. 103, No. 1, 02.05.2001, p. 46-50.

Research output: Contribution to journalArticle

Romaguera, Rita L. ; Minagar, Alireza ; Bruce, Jocelyn H. ; Jagid, Jonathan ; Falcone, Steven ; Curless, Richard G. ; Ragheb, John ; Morrison, Glenn. / Adrenocortical carcinoma with cerebral metastasis in a child : Case report and review of the literature. In: Clinical Neurology and Neurosurgery. 2001 ; Vol. 103, No. 1. pp. 46-50.
@article{9caafd6e5989403a8df8d3629bf48d6b,
title = "Adrenocortical carcinoma with cerebral metastasis in a child: Case report and review of the literature",
abstract = "Objective and importance: Adrenocortical carcinoma (ACC) is rare in the pediatric population, and brain metastasis seldom occurs. Clinical presentation: The authors report a case of metastatic ACC to the brain in a 9-year-old patient who had an adrenal cortex neoplasm removed at 4 years of age, and was free of symptoms for 5 years. Two weeks before admission she complained of blurred vision in both eyes. Intervention: Examination revealed bilateral papilledema, and a Magnetic Resonance Imaging (MRI) of the brain revealed a mass in the left lateral ventricle with extensive vasogenic edema and hydrocephalus. The tumor was removed, and histopathologic examination demonstrated metastatic ACC. Conclusion: Although ACC is a rare neoplasm it must be considered in the differential diagnosis of cerebral lesions in patients with a history of this tumor. Periodic long-term brain imaging is suggested as part of the follow up in patients with adrenocortical neoplasms.",
keywords = "Adrenocortical carcinoma, Adrenocortical neoplasm, Brain metastasis, Brain tumor",
author = "Romaguera, {Rita L.} and Alireza Minagar and Bruce, {Jocelyn H.} and Jonathan Jagid and Steven Falcone and Curless, {Richard G.} and John Ragheb and Glenn Morrison",
year = "2001",
month = "5",
day = "2",
doi = "10.1016/S0303-8467(01)00105-6",
language = "English",
volume = "103",
pages = "46--50",
journal = "Clinical Neurology and Neurosurgery",
issn = "0303-8467",
publisher = "Elsevier",
number = "1",

}

TY - JOUR

T1 - Adrenocortical carcinoma with cerebral metastasis in a child

T2 - Case report and review of the literature

AU - Romaguera, Rita L.

AU - Minagar, Alireza

AU - Bruce, Jocelyn H.

AU - Jagid, Jonathan

AU - Falcone, Steven

AU - Curless, Richard G.

AU - Ragheb, John

AU - Morrison, Glenn

PY - 2001/5/2

Y1 - 2001/5/2

N2 - Objective and importance: Adrenocortical carcinoma (ACC) is rare in the pediatric population, and brain metastasis seldom occurs. Clinical presentation: The authors report a case of metastatic ACC to the brain in a 9-year-old patient who had an adrenal cortex neoplasm removed at 4 years of age, and was free of symptoms for 5 years. Two weeks before admission she complained of blurred vision in both eyes. Intervention: Examination revealed bilateral papilledema, and a Magnetic Resonance Imaging (MRI) of the brain revealed a mass in the left lateral ventricle with extensive vasogenic edema and hydrocephalus. The tumor was removed, and histopathologic examination demonstrated metastatic ACC. Conclusion: Although ACC is a rare neoplasm it must be considered in the differential diagnosis of cerebral lesions in patients with a history of this tumor. Periodic long-term brain imaging is suggested as part of the follow up in patients with adrenocortical neoplasms.

AB - Objective and importance: Adrenocortical carcinoma (ACC) is rare in the pediatric population, and brain metastasis seldom occurs. Clinical presentation: The authors report a case of metastatic ACC to the brain in a 9-year-old patient who had an adrenal cortex neoplasm removed at 4 years of age, and was free of symptoms for 5 years. Two weeks before admission she complained of blurred vision in both eyes. Intervention: Examination revealed bilateral papilledema, and a Magnetic Resonance Imaging (MRI) of the brain revealed a mass in the left lateral ventricle with extensive vasogenic edema and hydrocephalus. The tumor was removed, and histopathologic examination demonstrated metastatic ACC. Conclusion: Although ACC is a rare neoplasm it must be considered in the differential diagnosis of cerebral lesions in patients with a history of this tumor. Periodic long-term brain imaging is suggested as part of the follow up in patients with adrenocortical neoplasms.

KW - Adrenocortical carcinoma

KW - Adrenocortical neoplasm

KW - Brain metastasis

KW - Brain tumor

UR - http://www.scopus.com/inward/record.url?scp=0035058093&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035058093&partnerID=8YFLogxK

U2 - 10.1016/S0303-8467(01)00105-6

DO - 10.1016/S0303-8467(01)00105-6

M3 - Article

C2 - 11311478

AN - SCOPUS:0035058093

VL - 103

SP - 46

EP - 50

JO - Clinical Neurology and Neurosurgery

JF - Clinical Neurology and Neurosurgery

SN - 0303-8467

IS - 1

ER -