Adipocyte transplantation and stem cells: Plastic surgery meets regenerative medicine

Carlo Tremolada, Giancarlo Palmieri, Camillo Ricordi

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

The technologies for adipose tissue harvesting, processing, and transplantation have substantially evolved in the past two decades. Clinically driven advancements have paralleled a significant improvement in the understanding of cellular, molecular, and immunobiological events surrounding cell and tissue transplantation. These new mechanistic insights could be of assistance to better understand the mechanisms underlying some of the observed clinical improvements. In addition to plastic and reconstructive surgical applications, adipose tissue has become central to an increasing number of translational efforts involving adipose tissue derived progenitor cells. The growing interest in this area of research has resulted in the exploration of many novel research and clinical applications that utilize adipose tissue grafting and/or progenitor/stem cell derived cell products obtained from this tissue source. Progenitor, endothelial, and mesenchymal stem cells derived from adipose tissue could therefore not only be central to plastic and reconstructive surgery applications, but also become the focus of an array of therapeutic solutions for many disease conditions, such as those affecting bone, cartilage, muscle, liver, kidney, cardiac, neural, and the pancreas, expanding the possible indications and translational potential of tissue, cell-based, and regenerative medicine strategies.

Original languageEnglish
Pages (from-to)1217-1223
Number of pages7
JournalCell Transplantation
Volume19
Issue number10
DOIs
StatePublished - Dec 1 2010

Fingerprint

Regenerative Medicine
Stem Cell Transplantation
Plastic Surgery
Stem cells
Adipocytes
Surgery
Adipose Tissue
Tissue Transplantation
Tissue
Stem Cells
Reconstructive Surgical Procedures
Tissue and Organ Harvesting
Cell Transplantation
Mesenchymal Stromal Cells
Plastics
Transplantation (surgical)
Research
Cartilage
Pancreas
Liver

Keywords

  • Adipose
  • Fat
  • Graft
  • Lipofilling
  • Stem cell
  • Tissue remodeling

ASJC Scopus subject areas

  • Cell Biology
  • Transplantation
  • Biomedical Engineering

Cite this

Adipocyte transplantation and stem cells : Plastic surgery meets regenerative medicine. / Tremolada, Carlo; Palmieri, Giancarlo; Ricordi, Camillo.

In: Cell Transplantation, Vol. 19, No. 10, 01.12.2010, p. 1217-1223.

Research output: Contribution to journalArticle

Tremolada, Carlo ; Palmieri, Giancarlo ; Ricordi, Camillo. / Adipocyte transplantation and stem cells : Plastic surgery meets regenerative medicine. In: Cell Transplantation. 2010 ; Vol. 19, No. 10. pp. 1217-1223.
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