Abstract
The technologies for adipose tissue harvesting, processing, and transplantation have substantially evolved in the past two decades. Clinically driven advancements have paralleled a significant improvement in the understanding of cellular, molecular, and immunobiological events surrounding cell and tissue transplantation. These new mechanistic insights could be of assistance to better understand the mechanisms underlying some of the observed clinical improvements. In addition to plastic and reconstructive surgical applications, adipose tissue has become central to an increasing number of translational efforts involving adipose tissue derived progenitor cells. The growing interest in this area of research has resulted in the exploration of many novel research and clinical applications that utilize adipose tissue grafting and/or progenitor/stem cell derived cell products obtained from this tissue source. Progenitor, endothelial, and mesenchymal stem cells derived from adipose tissue could therefore not only be central to plastic and reconstructive surgery applications, but also become the focus of an array of therapeutic solutions for many disease conditions, such as those affecting bone, cartilage, muscle, liver, kidney, cardiac, neural, and the pancreas, expanding the possible indications and translational potential of tissue, cell-based, and regenerative medicine strategies.
| Original language | English |
|---|---|
| Pages (from-to) | 1217-1223 |
| Number of pages | 7 |
| Journal | Cell Transplantation |
| Volume | 19 |
| Issue number | 10 |
| DOIs | |
| State | Published - Dec 1 2010 |
Fingerprint
Keywords
- Adipose
- Fat
- Graft
- Lipofilling
- Stem cell
- Tissue remodeling
ASJC Scopus subject areas
- Cell Biology
- Transplantation
- Biomedical Engineering
Cite this
Adipocyte transplantation and stem cells : Plastic surgery meets regenerative medicine. / Tremolada, Carlo; Palmieri, Giancarlo; Ricordi, Camillo.
In: Cell Transplantation, Vol. 19, No. 10, 01.12.2010, p. 1217-1223.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Adipocyte transplantation and stem cells
T2 - Plastic surgery meets regenerative medicine
AU - Tremolada, Carlo
AU - Palmieri, Giancarlo
AU - Ricordi, Camillo
PY - 2010/12/1
Y1 - 2010/12/1
N2 - The technologies for adipose tissue harvesting, processing, and transplantation have substantially evolved in the past two decades. Clinically driven advancements have paralleled a significant improvement in the understanding of cellular, molecular, and immunobiological events surrounding cell and tissue transplantation. These new mechanistic insights could be of assistance to better understand the mechanisms underlying some of the observed clinical improvements. In addition to plastic and reconstructive surgical applications, adipose tissue has become central to an increasing number of translational efforts involving adipose tissue derived progenitor cells. The growing interest in this area of research has resulted in the exploration of many novel research and clinical applications that utilize adipose tissue grafting and/or progenitor/stem cell derived cell products obtained from this tissue source. Progenitor, endothelial, and mesenchymal stem cells derived from adipose tissue could therefore not only be central to plastic and reconstructive surgery applications, but also become the focus of an array of therapeutic solutions for many disease conditions, such as those affecting bone, cartilage, muscle, liver, kidney, cardiac, neural, and the pancreas, expanding the possible indications and translational potential of tissue, cell-based, and regenerative medicine strategies.
AB - The technologies for adipose tissue harvesting, processing, and transplantation have substantially evolved in the past two decades. Clinically driven advancements have paralleled a significant improvement in the understanding of cellular, molecular, and immunobiological events surrounding cell and tissue transplantation. These new mechanistic insights could be of assistance to better understand the mechanisms underlying some of the observed clinical improvements. In addition to plastic and reconstructive surgical applications, adipose tissue has become central to an increasing number of translational efforts involving adipose tissue derived progenitor cells. The growing interest in this area of research has resulted in the exploration of many novel research and clinical applications that utilize adipose tissue grafting and/or progenitor/stem cell derived cell products obtained from this tissue source. Progenitor, endothelial, and mesenchymal stem cells derived from adipose tissue could therefore not only be central to plastic and reconstructive surgery applications, but also become the focus of an array of therapeutic solutions for many disease conditions, such as those affecting bone, cartilage, muscle, liver, kidney, cardiac, neural, and the pancreas, expanding the possible indications and translational potential of tissue, cell-based, and regenerative medicine strategies.
KW - Adipose
KW - Fat
KW - Graft
KW - Lipofilling
KW - Stem cell
KW - Tissue remodeling
UR - http://www.scopus.com/inward/record.url?scp=78650913446&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78650913446&partnerID=8YFLogxK
U2 - 10.3727/096368910X507187
DO - 10.3727/096368910X507187
M3 - Article
C2 - 20444320
AN - SCOPUS:78650913446
VL - 19
SP - 1217
EP - 1223
JO - Cell Transplantation
JF - Cell Transplantation
SN - 0963-6897
IS - 10
ER -