ADHD symptoms in children with autistic disorder (AD)

H. H. Wright, S. A. Ravan, R. K. Abramson, C. M. Wolpert, S. L. Donnelly, M. A. Pericak-Vance, M. L. Cuccaro

Research output: Contribution to journalArticlepeer-review


Hyperactivity and inattention are commonly reported in children with AD, but there is little documentation of symptom frequency. Rutter and Lokyer (1967) reported overactivity in half of 63 children in a study of infantile psychosis. Ando and Yoshimora (1979) studied 47 children with autism and reported 36% had hyperactivity. Chong et al. (1990) reported 47% of 66 children with autism were hyperactive. We studied a group of children from a genetic study of AD to determine the frequency of hyperactivity and inattention reported by parents. Of 66 SNAP-IVs completed by parents, 31 (47%) of the individuals exceeded X+1SD for inattention while 20 (30%) exceeded X+2SD. For hyperactivity the numbers were 22 (33%) and 13 (20%) respectively. Parents also completed the Aberrant Behavior Checklist (ABC). The hyperactivity sub-scale of the ABC includes both hyperactivity and inattention questions. Of 138 children, 33 (24%) exceeded the 85th percentile for hyperactivity. For 37 children, the SNAP-IV and ABC were completed within 6 months. The correlation between the ABC hyperactivity sub-scale and the sum of the SNAP-IV hyperactivity and inattention scores was 0.65. Examination of the ADHD symptoms may prove useful in stratifying the data set for linkage analysis.

Original languageEnglish (US)
Number of pages1
JournalAmerican Journal of Medical Genetics - Neuropsychiatric Genetics
Issue number4
StatePublished - Aug 7 2000
Externally publishedYes

ASJC Scopus subject areas

  • Genetics(clinical)
  • Psychiatry and Mental health
  • Cellular and Molecular Neuroscience


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