Abstract
Adenosine has been reported to cause polymorphic VT in patients with congenital or acquired prolonged QT intervals and to cause pause dependent VT in a patient with a normal QT interval. There have been no previous reports of adenosine causing nonpause dependent polymorphic VT in patients without structural heart disease. We report two patients, with normal hearts and normal QT intervals, who developed nonsustained polymorphic VT that was not pause dependent. Adenosine induced polymorphic VT does not appear to be a marker of the long QT syndrome, but may be an uncommon yet not unexpected pharmacological response to drug administration.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 743-745 |
| Number of pages | 3 |
| Journal | PACE - Pacing and Clinical Electrophysiology |
| Volume | 20 |
| Issue number | 3 I |
| DOIs | |
| State | Published - Apr 5 1997 |
| Externally published | Yes |
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Keywords
- adenosine
- proarrhythmia
- ventricular tachycardia
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Adenosine induced polymorphic ventricular tachycardia in adults without structural heart disease. / Smith, Jeffrey R.; Goldberger, Jeffrey; Kadish, Alan H.
In: PACE - Pacing and Clinical Electrophysiology, Vol. 20, No. 3 I, 05.04.1997, p. 743-745.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Adenosine induced polymorphic ventricular tachycardia in adults without structural heart disease
AU - Smith, Jeffrey R.
AU - Goldberger, Jeffrey
AU - Kadish, Alan H.
PY - 1997/4/5
Y1 - 1997/4/5
N2 - Adenosine has been reported to cause polymorphic VT in patients with congenital or acquired prolonged QT intervals and to cause pause dependent VT in a patient with a normal QT interval. There have been no previous reports of adenosine causing nonpause dependent polymorphic VT in patients without structural heart disease. We report two patients, with normal hearts and normal QT intervals, who developed nonsustained polymorphic VT that was not pause dependent. Adenosine induced polymorphic VT does not appear to be a marker of the long QT syndrome, but may be an uncommon yet not unexpected pharmacological response to drug administration.
AB - Adenosine has been reported to cause polymorphic VT in patients with congenital or acquired prolonged QT intervals and to cause pause dependent VT in a patient with a normal QT interval. There have been no previous reports of adenosine causing nonpause dependent polymorphic VT in patients without structural heart disease. We report two patients, with normal hearts and normal QT intervals, who developed nonsustained polymorphic VT that was not pause dependent. Adenosine induced polymorphic VT does not appear to be a marker of the long QT syndrome, but may be an uncommon yet not unexpected pharmacological response to drug administration.
KW - adenosine
KW - proarrhythmia
KW - ventricular tachycardia
UR - http://www.scopus.com/inward/record.url?scp=0030999778&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030999778&partnerID=8YFLogxK
U2 - 10.1111/j.1540-8159.1997.tb03897.x
DO - 10.1111/j.1540-8159.1997.tb03897.x
M3 - Article
VL - 20
SP - 743
EP - 745
JO - PACE - Pacing and Clinical Electrophysiology
JF - PACE - Pacing and Clinical Electrophysiology
SN - 0147-8389
IS - 3 I
ER -