Adenocarcinoma of the prostate. Stage-by-stage treatment alternatives

M. S. Soloway

Research output: Contribution to journalArticle

Abstract

The best treatment for adenocarcinoma of the prostate depends on the patient's age, general medical condition, life expectancy, and willingness to accept such side effects as impotence. Radical prostatectomy or full-dose radiation therapy are usually curative when cancer is confined to the gland. The technique of prostatectomy has been improved and potency often can be preserved. One the tumor extends beyond the gland, treatment alternatives are radiation or endocrine therapy. If lymph nodes are negative, radiation therapy may result in a long period without progression. If lymph nodes are positive, the expense and morbidity of radiation therapy may not be worthwhile because the likelihood of cure is low. Androgen deprivation, or endocrine manipulation, is preferred for metastatic disease. Response is varied and may depend on the patient's testosterone level when therapy is initiated. Survival is shorter in those with levels below normal.

Original languageEnglish
Pages (from-to)44-55
Number of pages12
JournalPostgraduate Medicine
Volume84
Issue number7
StatePublished - Jan 1 1988
Externally publishedYes

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Prostate
Adenocarcinoma
Radiotherapy
Prostatectomy
Lymph Nodes
Erectile Dysfunction
Therapeutics
Life Expectancy
Androgens
Testosterone
Neoplasms
Radiation
Morbidity
Survival

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Adenocarcinoma of the prostate. Stage-by-stage treatment alternatives. / Soloway, M. S.

In: Postgraduate Medicine, Vol. 84, No. 7, 01.01.1988, p. 44-55.

Research output: Contribution to journalArticle

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