Addressing dual diagnosis patients suffering from attention-deficit hyperactivity disorders and comorbid substance use disorders: A review of treatment considerations

Jose Martinez-Raga, Carlos Knecht, Raquel De Alvaro, Nestor Szerman, Pedro Ruiz

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

To provide an updated, thorough, and critical review of the current status of the pharmacological and psychosocial treatments of patients with attentiondeficit hyperactivity disorder (ADHD) and a comorbid substance use disorder (SUD). Methods: Comprehensive and systematic search of relevant databases (Medline, PubMed, Embase, and the Cochrane Library of systematic reviews and clinical trials) was carried out until January 31, 2012. Results: Treatment of patients with ADHD and a comorbid SUD is based on a multimodal and integrated approach, requiring the adequate management of the comorbid disorders, with psychosocial and pharmacological treatments. Regarding the pharmacotherapies for ADHD, prescription psychostimulants, particularly methylphenidate and atomoxetine, have all been assessed in dually diagnosed patients, for treating the symptoms of ADHD or for managing the comorbid SUD. Overall, medications are safe, well tolerated, and provide short-term and long-term benefits in patients with ADHD and comorbid SUD. Conclusions: Studies assessing the efficacy of pharmacotherapies for ADHD have shown that they are equally efficacious and well tolerated, generally in combination with psychological interventions, in patients with a comorbid SUD. In addition, psychostimulant treatment of children with ADHD appears to have a protective effect on the subsequent risk for SUD.

Original languageEnglish (US)
Pages (from-to)213-230
Number of pages18
JournalAddictive Disorders and their Treatment
Volume12
Issue number4
DOIs
StatePublished - Dec 1 2013

Keywords

  • Addiction
  • ADHD
  • Dual disorders
  • Substance use disorders
  • Treatment

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Psychiatry and Mental health

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