Acute tumor lysis syndrome after proximal splenic artery embolization

Jason T. Salsamendi, Mehul H. Doshi, Francisco J. Gortes, Joe U. Levi, Govindarajan Narayanan

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Preoperative splenic artery embolization for massive splenomegaly has been shown to reduce intraoperative hemorrhage during splenectomy. We describe a case of tumor lysis syndrome after proximal splenic artery embolization in a patient with advanced mantle cell lymphoma and splenic involvement. The patient presented initially with hyperkalemia two days after embolization that worsened during splenectomy. He was stabilized, but developed laboratory tumor lysis syndrome with renal failure and expired. High clinical suspicion of tumor lysis syndrome in this setting is advised. Treatment must be started early to avoid serious renal injury and death. Lastly, same day splenectomy and embolization should be considered to decrease the likelihood of developing tumor lysis syndrome.

Original languageEnglish (US)
Pages (from-to)90-92
Number of pages3
JournalRadiology Case Reports
Issue number2
StatePublished - Jun 1 2016


  • Hyperkalemia
  • Mantle cell lymphoma
  • Proximal splenic artery embolization
  • Splenectomy
  • Splenic artery embolization
  • Splenomegaly
  • Tumor lysis syndrome

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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