Acute symptomatic peri-lead edema 33 hours after deep brain stimulation surgery: a case report

Nathan B. Schoen, Walter J. Jermakowicz, Corneliu C. Luca, Jonathan R. Jagid

Research output: Contribution to journalArticle

6 Scopus citations


Background: Symptomatic peri-lead edema is a rare complication of deep brain stimulation that has been reported to develop 4 to 120 days postoperatively. Case presentation: Here we report the case of a 63-year-old Hispanic man with an 8-year history of Parkinson’s disease who underwent bilateral placement of subthalamic nucleus deep brain stimulation leads and presented with acute, symptomatic, unilateral, peri-lead edema just 33 hours after surgery. Conclusions: We document a thorough radiographic time course showing the evolution of these peri-lead changes and their regression with steroid therapy, and discuss the therapeutic implications of these findings. We propose that the unilateral peri-lead edema after bilateral deep brain stimulation is the result of severe microtrauma with blood-brain barrier disruption. Knowledge of such early manifestation of peri-lead edema after deep brain stimulation is critical for ruling out stroke and infection and preventing unnecessary diagnostic testing or hardware removal in this rare patient population.

Original languageEnglish (US)
Article number103
JournalJournal of medical case reports
Issue number1
StatePublished - Apr 14 2017


  • Case report
  • Parkinson’s disease
  • Steroids
  • Surgical complication

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Acute symptomatic peri-lead edema 33 hours after deep brain stimulation surgery: a case report'. Together they form a unique fingerprint.

Cite this