Acute retinal necrosis caused by reactivation of herpes simplex virus type 2

W. S. Thompson, William W Culbertson, William E Smiddy, J. E. Robertson, J. T. Rosenbaum

Research output: Contribution to journalArticle

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Abstract

Acute retinal necrosis is a severe form of necrotizing retinitis. Acute retinal necrosis has been demonstrated to be caused by varicella-zoster virus and herpes simplex virus type 1. We treated three patients with acute retinal necrosis apparently caused by recrudescence of latent herpes simplex virus type 2. Primary viral infection was probably congenital, with documented perinatal herpes simplex virus type 2 infection in two patients. Bilateral chorioretinal scars were present in two patients, neither of whom had a history of ocular herpetic infection, suggesting that earlier subclinical chorioretinitis had occurred. In each case, periocular trauma preceded the development of retinitis by two to three weeks. These cases are evidently caused by trauma-induced reactivation of latent virus rather than the onset of a primary infection.

Original languageEnglish
Pages (from-to)205-211
Number of pages7
JournalAmerican Journal of Ophthalmology
Volume118
Issue number2
StatePublished - Jan 1 1994

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Acute Retinal Necrosis Syndrome
Human Herpesvirus 2
Retinitis
Virus Diseases
Chorioretinitis
Eye Infections
Human Herpesvirus 3
Wounds and Injuries
Human Herpesvirus 1
Cicatrix
Viruses
Recurrence
Infection

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Acute retinal necrosis caused by reactivation of herpes simplex virus type 2. / Thompson, W. S.; Culbertson, William W; Smiddy, William E; Robertson, J. E.; Rosenbaum, J. T.

In: American Journal of Ophthalmology, Vol. 118, No. 2, 01.01.1994, p. 205-211.

Research output: Contribution to journalArticle

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