Acute postoperative pain predicts chronic pain and long-term analgesic requirements after breast surgery for cancer

A. Fassoulaki, A. Melemeni, C. Staikou, A. Triga, C. Sarantopoulos

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Postoperative pain and analgesic requirements may be associated with chronic pain. The aim of the study was to investigate this association. We studied 98 patients who had cancer breast surgery and served as controls in four previous studies, receiving placebo. We compared the pain and analgesic requirements 0-9 h and 1-6 days postoperatively: a) between patients with chronic pain 3 months postoperatively versus patients without and b) between those patients who consumed analgesics at home versus those who did not. Patients with chronic pain had experienced higher intensity pain at rest the first 9 postoperative hours (VAS-rest p = 0.033). Patients requiring analgesics at home had consumed postoperatively more opioids (p = 0.005) and more paracetamol (p = 0.037). These patients had experienced pain of higher intensity the first 9 postoperative hours (VAS-rest p = 0.022, VAS-movement p = 0.009) as well as during the six postoperative days (VAS-rest p = 0.013, VAS-movement p = 0.001). Higher intensities of acute postoperative pain are associated with chronic pain development. Higher analgesic needs and higher acute postoperatively pain intensity are associated with long-term analgesic consumption.

Original languageEnglish (US)
Pages (from-to)241-248
Number of pages8
JournalActa anaesthesiologica Belgica
Volume59
Issue number4
StatePublished - Dec 1 2008
Externally publishedYes

Keywords

  • Analgesic requirements
  • Cancer breast surgery
  • Chronic pain
  • Postoperative pain

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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