Abstract
Postoperative pain and analgesic requirements may be associated with chronic pain. The aim of the study was to investigate this association. We studied 98 patients who had cancer breast surgery and served as controls in four previous studies, receiving placebo. We compared the pain and analgesic requirements 0-9 h and 1-6 days postoperatively: a) between patients with chronic pain 3 months postoperatively versus patients without and b) between those patients who consumed analgesics at home versus those who did not. Patients with chronic pain had experienced higher intensity pain at rest the first 9 postoperative hours (VAS-rest p = 0.033). Patients requiring analgesics at home had consumed postoperatively more opioids (p = 0.005) and more paracetamol (p = 0.037). These patients had experienced pain of higher intensity the first 9 postoperative hours (VAS-rest p = 0.022, VAS-movement p = 0.009) as well as during the six postoperative days (VAS-rest p = 0.013, VAS-movement p = 0.001). Higher intensities of acute postoperative pain are associated with chronic pain development. Higher analgesic needs and higher acute postoperatively pain intensity are associated with long-term analgesic consumption.
| Original language | English |
|---|---|
| Pages (from-to) | 241-248 |
| Number of pages | 8 |
| Journal | Acta Anaesthesiologica Belgica |
| Volume | 59 |
| Issue number | 4 |
| State | Published - Dec 1 2008 |
| Externally published | Yes |
Fingerprint
Keywords
- Analgesic requirements
- Cancer breast surgery
- Chronic pain
- Postoperative pain
ASJC Scopus subject areas
- Anesthesiology and Pain Medicine
Cite this
Acute postoperative pain predicts chronic pain and long-term analgesic requirements after breast surgery for cancer. / Fassoulaki, A.; Melemeni, A.; Staikou, C.; Triga, A.; Sarantopoulos, Konstantinos D.
In: Acta Anaesthesiologica Belgica, Vol. 59, No. 4, 01.12.2008, p. 241-248.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Acute postoperative pain predicts chronic pain and long-term analgesic requirements after breast surgery for cancer
AU - Fassoulaki, A.
AU - Melemeni, A.
AU - Staikou, C.
AU - Triga, A.
AU - Sarantopoulos, Konstantinos D.
PY - 2008/12/1
Y1 - 2008/12/1
N2 - Postoperative pain and analgesic requirements may be associated with chronic pain. The aim of the study was to investigate this association. We studied 98 patients who had cancer breast surgery and served as controls in four previous studies, receiving placebo. We compared the pain and analgesic requirements 0-9 h and 1-6 days postoperatively: a) between patients with chronic pain 3 months postoperatively versus patients without and b) between those patients who consumed analgesics at home versus those who did not. Patients with chronic pain had experienced higher intensity pain at rest the first 9 postoperative hours (VAS-rest p = 0.033). Patients requiring analgesics at home had consumed postoperatively more opioids (p = 0.005) and more paracetamol (p = 0.037). These patients had experienced pain of higher intensity the first 9 postoperative hours (VAS-rest p = 0.022, VAS-movement p = 0.009) as well as during the six postoperative days (VAS-rest p = 0.013, VAS-movement p = 0.001). Higher intensities of acute postoperative pain are associated with chronic pain development. Higher analgesic needs and higher acute postoperatively pain intensity are associated with long-term analgesic consumption.
AB - Postoperative pain and analgesic requirements may be associated with chronic pain. The aim of the study was to investigate this association. We studied 98 patients who had cancer breast surgery and served as controls in four previous studies, receiving placebo. We compared the pain and analgesic requirements 0-9 h and 1-6 days postoperatively: a) between patients with chronic pain 3 months postoperatively versus patients without and b) between those patients who consumed analgesics at home versus those who did not. Patients with chronic pain had experienced higher intensity pain at rest the first 9 postoperative hours (VAS-rest p = 0.033). Patients requiring analgesics at home had consumed postoperatively more opioids (p = 0.005) and more paracetamol (p = 0.037). These patients had experienced pain of higher intensity the first 9 postoperative hours (VAS-rest p = 0.022, VAS-movement p = 0.009) as well as during the six postoperative days (VAS-rest p = 0.013, VAS-movement p = 0.001). Higher intensities of acute postoperative pain are associated with chronic pain development. Higher analgesic needs and higher acute postoperatively pain intensity are associated with long-term analgesic consumption.
KW - Analgesic requirements
KW - Cancer breast surgery
KW - Chronic pain
KW - Postoperative pain
UR - http://www.scopus.com/inward/record.url?scp=60849136025&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=60849136025&partnerID=8YFLogxK
M3 - Article
C2 - 19235522
AN - SCOPUS:60849136025
VL - 59
SP - 241
EP - 248
JO - Acta Anaesthesiologica Belgica
JF - Acta Anaesthesiologica Belgica
SN - 0001-5164
IS - 4
ER -