Acute phase protein and protein electrophoresis values for captive grant's zebra (equus burchelli)

Carolyn Cray, Elizabeth Hammond, Holly Haefele

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Grant's zebra (Equus burchelli) are commonly kept in zoos and are subject to routine health monitoring and research studies. Recently, assays for acute phase proteins (APP) have been described in many wildlife species, and specific assays for serum amyloid A (SAA) have been well validated and studied in horses (Equus ferus caballus), in which it serves as a major APP. In the present study, serum samples from 26 Grant's zebra were subject to analysis by using assays for SAA, haptoglobin (HP), and protein electrophoresis. Reference intervals were calculated by using the robust method: SAA 1.8-31.4 mg/L and HP 0.37-1.58 mg/ml. Significant differences in SAA and HP were observed in clinically abnormal zebra; in some cases, these differences were marked and were noted in the absence of abnormal values for protein electrophoretic fractions. These data indicate that APP may be a valuable and sensitive tool in monitoring inflammation in this species.

Original languageEnglish (US)
Pages (from-to)1107-1110
Number of pages4
JournalJournal of Zoo and Wildlife Medicine
Issue number4
StatePublished - Dec 1 2013


  • Electrophoresis
  • Equus burchelli
  • Grants zebra
  • haptoglobin
  • inflammation
  • serum amyloid

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)


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