Acute Myocardial Injury in Association with Metformin Toxicity

Ashish Garg; Nataly Sanchez-Solano; Sudheer Gorla; Sethuraman Swaminathan

doi:https://doi.org/10.1055/s-0038-1626698

Acute Myocardial Injury in Association with Metformin Toxicity

Ashish Garg, Nataly Sanchez-Solano, Sudheer Gorla, Sethuraman Swaminathan

Pediatrics

Research output: Contribution to journal › Article › peer-review

Abstract

Metformin is one of the most commonly used oral hypoglycemic agents in the
treatment of type 2 diabetes mellitus. Toxicity related to accidental or intentional
ingestion of metformin is well reported in the pediatric literature. We report a case of
transient acutemyocardial injury documented by biochemical and electrophysiological evidences in an adolescent male who presented with intentional ingestion of a large dose of metformin. To our knowledge, this is the first such case of documented reversible myocardial injury in relation to metformin toxicity to be reported in the pediatric literature.

Original language	English (US)
Pages (from-to)	169-172
Journal	Journal of Pediatric Intensive Care
Volume	7
Issue number	3
DOIs	https://doi.org/10.1055/s-0038-1626698
State	Published - Sep 2018

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https://doi.org/10.1055/s-0038-1626698

Cite this

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title = "Acute Myocardial Injury in Association with Metformin Toxicity",

abstract = "Metformin is one of the most commonly used oral hypoglycemic agents in thetreatment of type 2 diabetes mellitus. Toxicity related to accidental or intentionalingestion of metformin is well reported in the pediatric literature. We report a case oftransient acutemyocardial injury documented by biochemical and electrophysiological evidences in an adolescent male who presented with intentional ingestion of a large dose of metformin. To our knowledge, this is the first such case of documented reversible myocardial injury in relation to metformin toxicity to be reported in the pediatric literature.",

author = "Ashish Garg and Nataly Sanchez-Solano and Sudheer Gorla and Sethuraman Swaminathan",

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AU - Garg, Ashish

AU - Sanchez-Solano, Nataly

AU - Gorla, Sudheer

AU - Swaminathan, Sethuraman

PY - 2018/9

Y1 - 2018/9

N2 - Metformin is one of the most commonly used oral hypoglycemic agents in thetreatment of type 2 diabetes mellitus. Toxicity related to accidental or intentionalingestion of metformin is well reported in the pediatric literature. We report a case oftransient acutemyocardial injury documented by biochemical and electrophysiological evidences in an adolescent male who presented with intentional ingestion of a large dose of metformin. To our knowledge, this is the first such case of documented reversible myocardial injury in relation to metformin toxicity to be reported in the pediatric literature.

AB - Metformin is one of the most commonly used oral hypoglycemic agents in thetreatment of type 2 diabetes mellitus. Toxicity related to accidental or intentionalingestion of metformin is well reported in the pediatric literature. We report a case oftransient acutemyocardial injury documented by biochemical and electrophysiological evidences in an adolescent male who presented with intentional ingestion of a large dose of metformin. To our knowledge, this is the first such case of documented reversible myocardial injury in relation to metformin toxicity to be reported in the pediatric literature.

U2 - https://doi.org/10.1055/s-0038-1626698

DO - https://doi.org/10.1055/s-0038-1626698

M3 - Article

VL - 7

SP - 169

EP - 172

JO - Journal of Pediatric Intensive Care

JF - Journal of Pediatric Intensive Care

SN - 2146-4618

IS - 3

ER -

Acute Myocardial Injury in Association with Metformin Toxicity

Abstract

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